CAJ | 학술논문

目的探讨以体温作为阿托品化的定量指标抢救急性有机磷农药中毒(AOPP)的具体方法和价值.方法88例AOPP患者被随机分为治疗组和对照组.将体温分为四个阶段：<37℃；37℃~37.5℃；37.5℃~38℃；>38℃.给药策略：T<37℃,提示阿托品不足,给予大剂量阿托品；T升至37℃~37.5℃提示开始阿托品化,减量给予阿托品；T37.5℃~38℃,提示已阿托品化,大幅度减少阿托品用量；T>38℃提示已阿托品过量中毒,需暂停阿托品,待T降至37℃~37.5℃再开始给小剂量阿托品；若降至<37℃,重新给予较大剂量阿托品.结果该方法抢救AOPP的死亡率为6%,对照组为21%.结论以体温作为阿托品化的定量指标抢救AOPP,方法简便易行,能明显降低阿托品过量中毒和不足的死亡率.值得推广应用.
목적탐토이체온작위아탁품화적정량지표창구급성유궤린농약중독(AOPP)적구체방법화개치.방법88례AOPP환자피수궤분위치료조화대조조.장체온분위사개계단：<37℃；37℃~37.5℃；37.5℃~38℃；>38℃.급약책략：T<37℃,제시아탁품불족,급여대제량아탁품；T승지37℃~37.5℃제시개시아탁품화,감량급여아탁품；T37.5℃~38℃,제시이아탁품화,대폭도감소아탁품용량；T>38℃제시이아탁품과량중독,수잠정아탁품,대T강지37℃~37.5℃재개시급소제량아탁품；약강지<37℃,중신급여교대제량아탁품.결과해방법창구AOPP적사망솔위6%,대조조위21%.결론이체온작위아탁품화적정량지표창구AOPP,방법간편역행,능명현강저아탁품과량중독화불족적사망솔.치득추엄응용.
Objective To explore the specific methods and value. of temperature as atropinizaton quantitative index in treatment of acute organophosphorus pesticide poisoning (AOPP) Methods The 88 AOPP patients were randomly divided into treatment group and control group. The temperature was divided into:four stages: < 37 ℃; 37℃~37.5℃; 37.5℃~38℃; > 38℃..Dosing method: T < 37℃, indicating given atropine shortage ,to give larger doses of atropine; T rised to 37℃~37.5℃, indicating the atropinization had,been started,to reduce doses of atropine;T to 37.5℃~38℃, indicating atropinzation had been reacded, to greatly reduce the dosage of atropine;T > 38℃, indicating atropine overdose poisoning, to suspend the use of atropine, wait for T drops to 37℃~37.5℃ and began to give small doses of atropine;If T fell to <37℃, the larger doses of atropine are given again. results The method was used to treat the AOPP with a mortality rate of 6% in the therapy group, 21% in the control group. Conclusion the method on the temperature as atropine quantitative index in treatment of AOPP is simple and easy to operate, and can significantly reduce the mortality rate of overdose poisoning and insufficient dosage of atropine . It is popularization and application.