CAJ | 학술논문

目的探讨复方苦参注射液联合顺铂治疗恶性胸腔积液的效果.方法将86例恶性胸腔积液患者随机分为治疗组和对照组,患者均接受胸腔穿刺术放出积液,对照组胸腔内注射顺铂60 mg/m2,治疗组在对照组治疗基础上于胸腔内注射复方苦参注射液30ml.治疗1月后,观察两组疗效.结果与对照组比较,治疗组的有效缓解率明显提高,达83.7%,且不良反应明显减少,KPS评分明显提高,以上差异均具有统计学意义(P<0.05).结论苦参注射液联合顺铂胸腔灌注治疗恶性胸腔积液的疗效确切,不良反应少,患者耐受性好,值得推广.
목적탐토복방고삼주사액연합순박치료악성흉강적액적효과.방법장86례악성흉강적액환자수궤분위치료조화대조조,환자균접수흉강천자술방출적액,대조조흉강내주사순박60 mg/m2,치료조재대조조치료기출상우흉강내주사복방고삼주사액30ml.치료1월후,관찰량조료효.결과여대조조비교,치료조적유효완해솔명현제고,체83.7%,차불량반응명현감소,KPS평분명현제고,이상차이균구유통계학의의(P<0.05).결론고삼주사액연합순박흉강관주치료악성흉강적액적료효학절,불량반응소,환자내수성호,치득추엄.
Objective To observe clinical curative effect of intracavity Kushen injection combined with cisplatin for treating malignant pleural effusion. Methods 86 patients with malignant pleural effusion were randomly divided into two groups, after release the pleural effusion as possible, patients in experiment group were injected with Kushen injection combined with cisplatin, those in control group were taken injected with cisplatin alone. The clinical effects were observed in the two groups after 1 month. Results Compared with the control group, the value of RR and KPS were promoted obviously, and the untoward reaction rate was deceased. All of the changes were shown up significant difference(P<0.05). Conclusion Kushen injection combined with cisplatin is a reliable and safe way to treat the malignant pleural effusion.