CAJ | 학술논문

目的观察腰交感神经节射频热凝结合针刀治疗腰椎管狭窄症前后血清和尿液儿茶酚胺的变化.方法将100例腰椎管狭窄症的患者随机分为观察组和对照组，每组各50例，观察组采用腰交感神经节射频热凝结合针刀治疗；对照组采用电针治疗.采用荧光分光光度法测定治疗前后血清中去甲肾上腺素(NA)、多巴胺(DA)和尿液中的儿茶酚胺(CA)，多巴胺(DA)的含量.结果治疗前两组血清中NA、DA含量明显升高，治疗后两组血清中NA、DA含量均呈下降趋势，观察组下降更明显，与治疗前比较，有极显著性差异(P<0.01)，与对照组比较，有显著性差异(P<0.05).治疗后两组尿液中CA、DA含量均呈上升趋势，观察组上升更明显，与治疗前比较，有极著性差异(P<0.01)，与对照组比较，有显著性差异(P<0.05).结论腰交感神经节射频热凝结合针刀治疗对腰椎管狭窄症患者血清和尿液中儿茶酚胺含量有明显的良性调节作用.这可能是腰交感神经节射频热凝结合针刀治疗本病的作用机理之一.
목적관찰요교감신경절사빈열응결합침도치료요추관협착증전후혈청화뇨액인다분알적변화.방법장100례요추관협착증적환자수궤분위관찰조화대조조，매조각50례，관찰조채용요교감신경절사빈열응결합침도치료；대조조채용전침치료.채용형광분광광도법측정치료전후혈청중거갑신상선소(NA)、다파알(DA)화뇨액중적인다분알(CA)，다파알(DA)적함량.결과치료전량조혈청중NA、DA함량명현승고，치료후량조혈청중NA、DA함량균정하강추세，관찰조하강경명현，여치료전비교，유겁현저성차이(P<0.01)，여대조조비교，유현저성차이(P<0.05).치료후량조뇨액중CA、DA함량균정상승추세，관찰조상승경명현，여치료전비교，유겁저성차이(P<0.01)，여대조조비교，유현저성차이(P<0.05).결론요교감신경절사빈열응결합침도치료대요추관협착증환자혈청화뇨액중인다분알함량유명현적량성조절작용.저가능시요교감신경절사빈열응결합침도치료본병적작용궤리지일.
Objective:To observe the changes of serum and urine catecholamines in pateins of lumbar spinal canal stenosis with threatment of radiofrequency thermocoagulation at lumbar sympathetic ganglion combined with needle-knif. Methods:100 cases of lumbar spinal stenosis were randomly divided into observation group and control group, n = 50 cases, the observation group were treated with radiofrequency thermocoagulation at lumbar sympathetic ganglia combined with needle-knif; control group with EA treatment. Using the fluorescence spectrophotometry to determin noradrenaline (NA), dopamine (DA) in serum and catecholamine (CA), dopamine (DA) in urine at before and after treatment. Results: The two groups in serum before treatment of NA, DA content was significantly increased after treatment, the two groups in serum of NA of DA content showed a downward trend in the observation group decreased more significantly compared with before treatment, there was a significant difference (P <0.01).compared with the control group, a significant difference (P<0.05). After treatment in two groups of urine CA, DA levels showed an upward trend, the observation group increased significantly compared with before treatment, there is a very significant difference (P <0.01) compared with the control group, significant differences (P <0.05). Conclusions: Radiofrequency thermocoagulation of lumbar sympathetic ganglia combined with acupuncture therapy to the lumbar spinal canal stenosis in patients with serum and urine catecholamine levels in benign regulation. This may be one of the mechanisms that radiofrequency thermocoagulation of lumbar sympathetic ganglia combined with acupuncture therapy of this disease.