CAJ | 학술논문

目的探讨普贝生用于足月妊娠促宫颈成熟和引产的有效性及安全性.方法将本院2010年12月-2011年12月有引产指征的足月妊娠孕妇147例随机分成两组，研究组用普贝生，对照组用催产素静滴引产，比较两组产妇宫颈成熟度评分、临产时间、破膜时间、分娩时间、总产程时间、分娩情况和结局以及新生儿评分.结果普贝生组用于足月妊娠促宫颈成熟和引产效果明显优于对照组(P<0.01)，用药至临产时间显著短于对照组(P<0.01)，引产成功率高于对照组，对母婴影响无显著差别.结论普贝生是一种安全有效方便实惠的引产药物，对母婴没有明显不良影响，可在临床上应用.
목적탐토보패생용우족월임신촉궁경성숙화인산적유효성급안전성.방법장본원2010년12월-2011년12월유인산지정적족월임신잉부147례수궤분성량조，연구조용보패생，대조조용최산소정적인산，비교량조산부궁경성숙도평분、임산시간、파막시간、분면시간、총산정시간、분면정황화결국이급신생인평분.결과보패생조용우족월임신촉궁경성숙화인산효과명현우우대조조(P<0.01)，용약지임산시간현저단우대조조(P<0.01)，인산성공솔고우대조조，대모영영향무현저차별.결론보패생시일충안전유효방편실혜적인산약물，대모영몰유명현불량영향，가재림상상응용.
Objective To investigate the effectiveness and safety of propess in term pregnancy for cervical ripening and induction of labor. Method Put the 147 term pregnancy women (admitted to our hospital from 2010.12to 2011.12)having induction indication into two groups at random . propess was used in the study group and oxytoxin was used in the controlled group, then observing the differences in bishop cervical score, time of labor, total stage of labor ,condition and results in deliverying ,and baby apgar score. Result propess used in the study group is more effective than oxytoxin used in the controlled group(P<0.01),the time of labor is shorter obviously when the propess is used than that in the controlled group(P<0.01).The mission sucess ratio in the study group is larger than in the controlled group.The effect to both mother and baby has no significant difference. Conclusion propess is a safe and effective new drug used for cervical ripening and induction of labor .It has no significant side effects to both mother and baby.It can be used in the clinical application.