CAJ | 학술논문

非典型鳞状细胞(atypical squamous cells，ASC)自1943年被首次提出，历经1988，1991和2001年TBS (the Bethesda System)三版修订，非典型鳞状细胞被分为意义不明确的不典型鳞状细胞(ASC of undetermined significance，ASC-US)和不除外高度上皮内病变的不典型鳞状细胞[ASC cannot exclude high-grade squamous intraepithelial lesion (HSIL)，又称为ASC-H]，这两个术语已得到临床实践证实，用其作为诊断分类明显提高了宫颈巴氏细胞学临床使用性。诊断为ASC-US和ASC-H的患者行高危型人乳头状瘤病毒(high-risk types of human papillomavirus，HR HPV)检测后分组管理，使后续的处理及治疗更加人性化，提高了宫颈液基薄层细胞学筛查的可靠性，降低了人为的过度治疗，使宫颈细胞学筛查更具科学性、可行性。
비전형린상세포(atypical squamous cells，ASC)자1943년피수차제출，력경1988，1991화2001년TBS (the Bethesda System)삼판수정，비전형린상세포피분위의의불명학적불전형린상세포(ASC of undetermined significance，ASC-US)화불제외고도상피내병변적불전형린상세포[ASC cannot exclude high-grade squamous intraepithelial lesion (HSIL)，우칭위ASC-H]，저량개술어이득도림상실천증실，용기작위진단분류명현제고료궁경파씨세포학림상사용성。진단위ASC-US화ASC-H적환자행고위형인유두상류병독(high-risk types of human papillomavirus，HR HPV)검측후분조관리，사후속적처리급치료경가인성화，제고료궁경액기박층세포학사사적가고성，강저료인위적과도치료，사궁경세포학사사경구과학성、가행성。
The term of atypical squamous cells (ASC) was raised for the ifrst time in 1943, and has been revised three times atfer. The 2001 Bethesda System further classiifed ASC into two categories:ASC of undetermined signiifcance (ASC-US) and ASC cannot exclude high-grade squamous intraepithelial lesion (HSIL) (or ASC-H). This classiifcation has been conifrmed through clinical practice and it has increased cervical cytology diagnosis usability and accuracy. Women with ASC-US or ASC-H are divided into groups by high-risk types of human papillomavirus (HR HPV) testing, and then were handled by follow-up treatments. The new classiifed method improves the reliability of cervical cytology screen and minimizes the amount of treatments unnecessary, which has made the cervical cytology screen to be more scientiifc and feasible.