CAJ | 학술논문

目的探讨脑结节性硬化(Tuberous Sclerousis,TS)的CT和MRI表现特征及影像学诊断价值,为临床诊断提供科学依据.方法对46例脑结节性硬化患者作头部CT和MRI平扫及增强扫描.CT采用GE Hispeed NX/I型及SIEMENS SOMATOM Definition As 128层螺旋CT；MRI采用 Philips 0.5T及SIEMENS Symphony P 1.5T低温超导磁共振扫描仪.结果 CT扫描发现：(1)室管膜下结节40例,均为多发,其中34例结节数目在3-32个之间,共223个,6例结节数目多而细小；(2)皮质和皮质下结节6例,共54个,钙化44个,未钙化10个.另外,脑白质损害2例,均为两侧额顶叶白质区小片低密度灶；脑室扩大9例,主要为三脑室和双侧脑室扩大.MRI扫描发现：(1)25例室管膜下结节,共56个,未钙化结节35个,钙化结节21个；(2)脑白质损害12例,均为两侧额顶叶白质区长T1、长T2信号灶.侧脑室室管膜下巨细胞星形细胞瘤1例,并有皮质结节及白质异常.结论室管膜下结节、皮质结节、白质异常和脑萎缩是TS主要影像学表现,尤其是室管膜下结节,是TS特征性影像学表现.CT可作为TS影像学检查方法首选,MRI检查作为优势互补,二者对临床TS病例尤其是不典型病例的确诊具有可靠和独特的应用价值.
목적탐토뇌결절성경화(Tuberous Sclerousis,TS)적CT화MRI표현특정급영상학진단개치,위림상진단제공과학의거.방법대46례뇌결절성경화환자작두부CT화MRI평소급증강소묘.CT채용GE Hispeed NX/I형급SIEMENS SOMATOM Definition As 128층라선CT；MRI채용 Philips 0.5T급SIEMENS Symphony P 1.5T저온초도자공진소묘의.결과 CT소묘발현：(1)실관막하결절40례,균위다발,기중34례결절수목재3-32개지간,공223개,6례결절수목다이세소；(2)피질화피질하결절6례,공54개,개화44개,미개화10개.령외,뇌백질손해2례,균위량측액정협백질구소편저밀도조；뇌실확대9례,주요위삼뇌실화쌍측뇌실확대.MRI소묘발현：(1)25례실관막하결절,공56개,미개화결절35개,개화결절21개；(2)뇌백질손해12례,균위량측액정협백질구장T1、장T2신호조.측뇌실실관막하거세포성형세포류1례,병유피질결절급백질이상.결론실관막하결절、피질결절、백질이상화뇌위축시TS주요영상학표현,우기시실관막하결절,시TS특정성영상학표현.CT가작위TS영상학검사방법수선,MRI검사작위우세호보,이자대림상TS병례우기시불전형병례적학진구유가고화독특적응용개치.
Objective To investigate the CT and MRI features of brain tuberous sclerosis and imaging diagnostic value, provide a scientific basis for clinical diagnosis. Methods Head CT and MRI scanning was used in 46 cases of brain tuberous sclerosis patients. The CT machine was a GE Hispeed NX / I-type and SIEMENS SOMATOM Definition As 128. The MRI machine was philips 0.5T and SIEMENS Symphony P 1.5T. Results CT findings: (1)40 cases was Patient of subependymal tubers. The tubers of 34 cases was in 3 to 32,a total of 223.The tubers of 6 cases was small;(2) 6 cases was Patient of cortical and subcortical tubers, a total of 54,calcified 44, 10 non-calcified. In addition ,white matter damage of 2 cases are on both sides of the frontal and parietal lobe lesions.9 cases was ventriculomegaly. MRI findings: (1)25 cases was Patient of subependymal tubers, a total of 56,35non-calcified,calcified21;(2) White matter damage of 12 cases. Conclusion The subependymal tubers, cortical tubers, white matter abnormalities and brain atrophy was the TS main imaging features. CT could be used as the TS image examination method preferred, MRI examination as a supplement. The two methods had a reliable and unique value for final diagnosis cases of clinical TS, especially in borderline case.