中外女性健康(下半月)
中外女性健康(下半月)
중외녀성건강(하반월)
CHINESE-FOREIGN WOMEN'S HEALTH
2013年
5期
85-85,77
,共2页
压力性尿失禁%转化生长因子-β1%Ⅲ型胶原
壓力性尿失禁%轉化生長因子-β1%Ⅲ型膠原
압력성뇨실금%전화생장인자-β1%Ⅲ형효원
Stress urinary incontinence%TGF-β1%CollagenⅢ
目的:探讨阴道前壁组织中TGF-β1的表达与SUI的关联性研究。方法:采用免疫组化方法,测定30例压力性尿失禁患者(SUI组),并选择同期20例妇科良性病变而行子宫切除术者作为对照(对照组),于手术中取患者阴道前壁,采用免疫组织化学方法观察TGF-β1的表达。结果:TGF-β1在SUI组着色低、分布稀疏,表达均低于正常对照组(P<0.05)。结论:TGF-β1可能通过减少Ⅲ型胶原的合成而导致SUI的发生。
目的:探討陰道前壁組織中TGF-β1的錶達與SUI的關聯性研究。方法:採用免疫組化方法,測定30例壓力性尿失禁患者(SUI組),併選擇同期20例婦科良性病變而行子宮切除術者作為對照(對照組),于手術中取患者陰道前壁,採用免疫組織化學方法觀察TGF-β1的錶達。結果:TGF-β1在SUI組著色低、分佈稀疏,錶達均低于正常對照組(P<0.05)。結論:TGF-β1可能通過減少Ⅲ型膠原的閤成而導緻SUI的髮生。
목적:탐토음도전벽조직중TGF-β1적표체여SUI적관련성연구。방법:채용면역조화방법,측정30례압력성뇨실금환자(SUI조),병선택동기20례부과량성병변이행자궁절제술자작위대조(대조조),우수술중취환자음도전벽,채용면역조직화학방법관찰TGF-β1적표체。결과:TGF-β1재SUI조착색저、분포희소,표체균저우정상대조조(P<0.05)。결론:TGF-β1가능통과감소Ⅲ형효원적합성이도치SUI적발생。
Objective To investigate the relationship between TGF-β1 and stress urinary incontinence. Methods:Immunohistochemical method was used, selecting 30 cases of stress urinary incontinence (SUI group) and 20 cases of benign gynecological disease and hysterectomy as control (control group) in the same period. The anterior vaginal wall of patients were taken in the process of surgery and subject to the observation of TGF-β1 expression. Results: TGF-β1 expression in SUI group is low and sparse,were lower than the normal control group (P<0.05). Conclusion:TGF-β1 cause SUI possibly by reducing the synthesis of CollagenⅢ.