现代农药
現代農藥
현대농약
MODERN AGROCHEMICALS
2013年
5期
22-24,34
,共4页
于康平%徐昶辉%李翔宇%徐韶康%李楠
于康平%徐昶輝%李翔宇%徐韶康%李楠
우강평%서창휘%리상우%서소강%리남
(R)-(-)-α-异丙基-4-氯苯乙酸二乙胺盐%消旋%利用
(R)-(-)-α-異丙基-4-氯苯乙痠二乙胺鹽%消鏇%利用
(R)-(-)-α-이병기-4-록분을산이을알염%소선%이용
diethylamine (R)-(-)-α-isopropyl-4-chlorophenyl acetate%racemization%utilization
研究了(R)-(-)-α-异丙基-4-氯苯乙酸二乙胺盐的消旋利用工艺，不需要溶剂和添加碱或酸，直接回流反应5 h可消旋化得到(±)-α-异丙基-4-氯苯乙酸，其质量分数大于98%，比旋光度[20α]D＝0。该消旋产物经过拆分得到(S)-(+)-α-异丙基-4-氯苯乙酸，完全适用于S-氰戊菊酯的合成。
研究瞭(R)-(-)-α-異丙基-4-氯苯乙痠二乙胺鹽的消鏇利用工藝，不需要溶劑和添加堿或痠，直接迴流反應5 h可消鏇化得到(±)-α-異丙基-4-氯苯乙痠，其質量分數大于98%，比鏇光度[20α]D＝0。該消鏇產物經過拆分得到(S)-(+)-α-異丙基-4-氯苯乙痠，完全適用于S-氰戊菊酯的閤成。
연구료(R)-(-)-α-이병기-4-록분을산이을알염적소선이용공예，불수요용제화첨가감혹산，직접회류반응5 h가소선화득도(±)-α-이병기-4-록분을산，기질량분수대우98%，비선광도[20α]D＝0。해소선산물경과탁분득도(S)-(+)-α-이병기-4-록분을산，완전괄용우S-청무국지적합성。
Racemization technology of diethylamine (R)-(-)-α-isopropyl-4-chlorophenyl acetate and its application were studied in this paper. (±)-α-isopropyl-4-chlorobenzene acetic acid could be obtained by refluxing 5 hours without solvent, alkali and acid, and the content of racemate was more than 98%, 20D[α] =0. (S)-(+)-α-isopropyl-4-chlorobenzene acetic acid was obtained by separating (±)-α-isopropyl-4-chlorobenzene acetic acid and completely suitable to synthe-size esfenvalerate.
