CAJ | 학술논문

增龄过程中，骨骼肌的衰退是一种自然而且不可避免的生理变化现象。为了全面、充分地认识和了解骨骼肌在增龄过程中的变化，从宏观到微观的角度，分析了国内外有关人和动物增龄过程中，骨骼肌组成及肌细胞变化（如肌质网释放Ca2＋浓度及肌原纤维收缩力的降低）等方面的相关研究结果。旨在为该领域的进一步研究提供参考，并为预防和干预老年人骨骼肌衰老提供理论依据。
증령과정중，골격기적쇠퇴시일충자연이차불가피면적생리변화현상。위료전면、충분지인식화료해골격기재증령과정중적변화，종굉관도미관적각도，분석료국내외유관인화동물증령과정중，골격기조성급기세포변화（여기질망석방Ca2＋농도급기원섬유수축력적강저）등방면적상관연구결과。지재위해영역적진일보연구제공삼고，병위예방화간예노년인골격기쇠로제공이론의거。
The age-related degeneration of skeletal muscles is a normal physiological phenomenon .This paper has summarized the research results concerning with the age-related degeneration of skeletal muscles on the basis of literature review.The age-related change in the composition of skeletal muscles , the decrease in the amount of Ca2+released from endoplasmic reticulum , and the decrease in the tension generated by myofibril have been analyzed with respect to the degeneration of skeletal muscles .It is expected that the current work would stimulate further detailed studies on the mechanism of skeletal muscles senescence and provide theoretical guidance for preventing and intervening muscle senescence .