分子诊断与治疗杂志
分子診斷與治療雜誌
분자진단여치료잡지
JOURNAL OF MOLECULAR DIAGNOSIS AND THERAPY
2013年
5期
306-310
,共5页
中青年%肥胖%高血压%患病率%同型半胱氨酸
中青年%肥胖%高血壓%患病率%同型半胱氨痠
중청년%비반%고혈압%환병솔%동형반광안산
Middle age%Obesity%Hypertension%Prevalence%Homocysteine
目的探讨中青年超重和肥胖对高血压各亚型患病率的影响。方法选取2012年9月在我院进行体检的某单位职工为研究对象，分析其中具有完整身高、体重、血压测量资料和生化指标且未服用降压药物的共计300名研究对象的结果。比较中青年超重和肥胖对高血压各亚型患病率和血清同型半胱氨酸（Hcy）水平的影响。结果该单位员工的超重和肥胖率分别达到35%和10.33%，男性更高，30~49岁间是超重和肥胖的患病高峰。随着BMI水平增加，男性和女性的收缩压、舒张压均值和血Hcy水平逐渐升高，在超重和肥胖组中，血压的性别差异消失。肥胖组血Hcy的性别差异消失。该单位员工总体高血压患病率为16%，在超重和肥胖组中分别达到20%和45.16%,收缩期和舒张期联合高血压（SDH）和单纯舒张期高血压（IDH）患病率高于单纯收缩期高血压（ISH）。30~49岁的中青年人群高血压亚型以SDH和IDH为主。2/3以上的超重或肥胖合并SDH或IDH是分布在中青年人群。37.5%和42.85%的30~49岁肥胖者合并高Hcy血症。结论超重和肥胖人群中血压和同型半胱氨酸的性别差异消失，高血压亚型以SDH和IDH为主，大多数的超重或肥胖合并SDH或IDH发生在30~49岁的中青年，应重点针对这部分人群开展综合健康促进措施防治高血压和高同型半胱氨酸血症。
目的探討中青年超重和肥胖對高血壓各亞型患病率的影響。方法選取2012年9月在我院進行體檢的某單位職工為研究對象，分析其中具有完整身高、體重、血壓測量資料和生化指標且未服用降壓藥物的共計300名研究對象的結果。比較中青年超重和肥胖對高血壓各亞型患病率和血清同型半胱氨痠（Hcy）水平的影響。結果該單位員工的超重和肥胖率分彆達到35%和10.33%，男性更高，30~49歲間是超重和肥胖的患病高峰。隨著BMI水平增加，男性和女性的收縮壓、舒張壓均值和血Hcy水平逐漸升高，在超重和肥胖組中，血壓的性彆差異消失。肥胖組血Hcy的性彆差異消失。該單位員工總體高血壓患病率為16%，在超重和肥胖組中分彆達到20%和45.16%,收縮期和舒張期聯閤高血壓（SDH）和單純舒張期高血壓（IDH）患病率高于單純收縮期高血壓（ISH）。30~49歲的中青年人群高血壓亞型以SDH和IDH為主。2/3以上的超重或肥胖閤併SDH或IDH是分佈在中青年人群。37.5%和42.85%的30~49歲肥胖者閤併高Hcy血癥。結論超重和肥胖人群中血壓和同型半胱氨痠的性彆差異消失，高血壓亞型以SDH和IDH為主，大多數的超重或肥胖閤併SDH或IDH髮生在30~49歲的中青年，應重點針對這部分人群開展綜閤健康促進措施防治高血壓和高同型半胱氨痠血癥。
목적탐토중청년초중화비반대고혈압각아형환병솔적영향。방법선취2012년9월재아원진행체검적모단위직공위연구대상，분석기중구유완정신고、체중、혈압측량자료화생화지표차미복용강압약물적공계300명연구대상적결과。비교중청년초중화비반대고혈압각아형환병솔화혈청동형반광안산（Hcy）수평적영향。결과해단위원공적초중화비반솔분별체도35%화10.33%，남성경고，30~49세간시초중화비반적환병고봉。수착BMI수평증가，남성화녀성적수축압、서장압균치화혈Hcy수평축점승고，재초중화비반조중，혈압적성별차이소실。비반조혈Hcy적성별차이소실。해단위원공총체고혈압환병솔위16%，재초중화비반조중분별체도20%화45.16%,수축기화서장기연합고혈압（SDH）화단순서장기고혈압（IDH）환병솔고우단순수축기고혈압（ISH）。30~49세적중청년인군고혈압아형이SDH화IDH위주。2/3이상적초중혹비반합병SDH혹IDH시분포재중청년인군。37.5%화42.85%적30~49세비반자합병고Hcy혈증。결론초중화비반인군중혈압화동형반광안산적성별차이소실，고혈압아형이SDH화IDH위주，대다수적초중혹비반합병SDH혹IDH발생재30~49세적중청년，응중점침대저부분인군개전종합건강촉진조시방치고혈압화고동형반광안산혈증。
Objective To explore the effect of the young and middle-aged overweight and obesity on the prevalence of hypertension subtype. Methods We selected 300 subjects who had medical examination and without taking antihypertensive drugs in our hospital in Sep 2012, and analysed complete data containing height, weight, blood pressure measurements and biochemical parameters. Compared the effect of young and middle-aged overweight and obesity on the prevalence of hypertension subtypes and serum homocysteine (Hcy) levels. Results The overweight rate and obesity rate were 35% and 10.33%, respectively, and the male is higher. The peak prevalence of overweight and obesity in the age of 30 to 49. Male and female systolic blood pressure, diastolic blood pressure and mean blood Hcy levels were gradually increased with the increasing of BMI levels. In overweight and obesity group, gender differences disappeared in blood pressure. In obesity group, Hcy levels had no difference in different gender. The total hypertension prevalence rate was 16%, and the overweight and obese group reached 20%and 45.16%, respectively. The prevalence rate systolic and diastolic hypertension (SDH) and isolated diastolic hypertension (IDH) higher than that of isolated systolic hypertension (ISH). SDH and IDH were the main hypertension subtypes in the age of 30 to 49 populations. 2/3 of the overweight or obese combined SDH or IDH were distributed in young and middle-aged crowd. There were 37.5%and 42.85%obese subjects had hyperhomocysteinemia in the age of 30~49. Conclusion There was no sexual difference of blood pressure and serum homocysteine in overweight and obesity group. The main hypertension subtypes were SDH and IDH. The majority of overweight or obesity subjects combined with SDH or IDH were distributed in 30~49 years old. These people should be intensively offered healthy promotion measurements to prevent hypertension and hyperhomocysteinemia..
