CAJ | 학술논문

目的：应用超声心动图来评价心脏再同步化治疗（CRT）心力衰竭患者的疗效。方法16例慢性心力衰竭患者行CRT植入，于术后1周、3个月、6个月对AV 和VV间期进行优化，观察术前及术后1周、3个月、6个月左心室舒张末、收缩末的直径（ LVDD、LVDS）及左室舒张、收缩末期容积（LVEDV 、LVESV）和左室射血分数（LVEF），及心脏同步化指标的变化。结果与术前比较，术后3个月、6个月心功能均得到改善，6 min步行距离增加，LVEF增加，LVDD、LVDS、LVEDV 和LVESV缩小，心脏同步化指标得到改善。结论在超声指导下对AV、VV 间期进行优化后心脏再同步化治疗可改善双心室的同步性和心脏功能。
목적：응용초성심동도래평개심장재동보화치료（CRT）심력쇠갈환자적료효。방법16례만성심력쇠갈환자행CRT식입，우술후1주、3개월、6개월대AV 화VV간기진행우화，관찰술전급술후1주、3개월、6개월좌심실서장말、수축말적직경（ LVDD、LVDS）급좌실서장、수축말기용적（LVEDV 、LVESV）화좌실사혈분수（LVEF），급심장동보화지표적변화。결과여술전비교，술후3개월、6개월심공능균득도개선，6 min보행거리증가，LVEF증가，LVDD、LVDS、LVEDV 화LVESV축소，심장동보화지표득도개선。결론재초성지도하대AV、VV 간기진행우화후심장재동보화치료가개선쌍심실적동보성화심장공능。
Objective To observe the effects of cardiac resynchronization therapy(CRT)on the cardiac function in patients with chronic heart failure by echocardiography.Methods Sixteen patients with chronic heart failure were assigned to CRT.The AV and VV delay were opti-mized by echocardiography at one week,three months and six months after operation,respectively.The left ventricular end-diastolic dimension (LVDD),end-contractive dimension(LVDS),the left ventricular end-diastolic volume (LVEDV)and left ventricular end-systolic volume (LVESV),left ventricular ejection fraction (LVEF)and the distance walked in six minutes were measured and compared before CRT opera-tion,at one week,three months and six months after CRT operation.The changes of synchrony cardiac index were also observed.Results Compared with pre-CRT,the patients experienced an improvement in the NYHA functional class and synchrony cardiac index,with the dis-tance walked in six minutes elongated,the LVEF raised,the LVDD,LVDS,LVEDV and LVESV decreased.Conclusions CRT results in sig-nificant clinical improvement in patients’biventricular mechanical synchrony and cardiac function after AV,VV delay optimizing guided by echocardiography.