中外健康文摘
中外健康文摘
중외건강문적
WORLD HEALTH DIGEST
2013年
7期
45-46,47
,共3页
高艳艳%高福生%刘永全%张增华
高豔豔%高福生%劉永全%張增華
고염염%고복생%류영전%장증화
慢性气道疾病%持续喘息%病原学
慢性氣道疾病%持續喘息%病原學
만성기도질병%지속천식%병원학
Chronic airway disease%Persistent wheezing%Aetiology
目的明确慢性气道疾病患者伴发持续性喘息是否与气道定植菌、感染菌有关联，其可能的病原体分布和构成与不伴持续喘息的慢性气道疾病患者有何异同。方法搜集符合诊断标准的患者39例，对照组42例。入选病例均提供基本资料，并行血常规、胸部X线或CT检查、肺功能检查、痰细菌学检测、非典型病原体血清学检测、真菌培养。结果病例组痰真菌培养阳性率为76.9%，细菌阳性率为35.9%，真菌构成中念珠菌21例，曲霉菌10例；而对照组痰真菌培养阳性率为26.2%，细菌阳性率为33.3%，真菌构成全部为念珠菌。结论慢性气道疾病并持续喘息患者的病原学构成以真菌为主，部分患者合并有细菌感染；其并发持续喘息的危险因素可能为痰真菌培养阳性；曲霉菌可能是导致患者持续喘息的主要真菌菌种。
目的明確慢性氣道疾病患者伴髮持續性喘息是否與氣道定植菌、感染菌有關聯，其可能的病原體分佈和構成與不伴持續喘息的慢性氣道疾病患者有何異同。方法搜集符閤診斷標準的患者39例，對照組42例。入選病例均提供基本資料，併行血常規、胸部X線或CT檢查、肺功能檢查、痰細菌學檢測、非典型病原體血清學檢測、真菌培養。結果病例組痰真菌培養暘性率為76.9%，細菌暘性率為35.9%，真菌構成中唸珠菌21例，麯黴菌10例；而對照組痰真菌培養暘性率為26.2%，細菌暘性率為33.3%，真菌構成全部為唸珠菌。結論慢性氣道疾病併持續喘息患者的病原學構成以真菌為主，部分患者閤併有細菌感染；其併髮持續喘息的危險因素可能為痰真菌培養暘性；麯黴菌可能是導緻患者持續喘息的主要真菌菌種。
목적명학만성기도질병환자반발지속성천식시부여기도정식균、감염균유관련，기가능적병원체분포화구성여불반지속천식적만성기도질병환자유하이동。방법수집부합진단표준적환자39례，대조조42례。입선병례균제공기본자료，병행혈상규、흉부X선혹CT검사、폐공능검사、담세균학검측、비전형병원체혈청학검측、진균배양。결과병례조담진균배양양성솔위76.9%，세균양성솔위35.9%，진균구성중념주균21례，곡매균10례；이대조조담진균배양양성솔위26.2%，세균양성솔위33.3%，진균구성전부위념주균。결론만성기도질병병지속천식환자적병원학구성이진균위주，부분환자합병유세균감염；기병발지속천식적위험인소가능위담진균배양양성；곡매균가능시도치환자지속천식적주요진균균충。
Objective:To make clear the correlation between the persistent wheezing in patients with chronic airway disease and colonization bacteria or infect bacteria, the difference of the possible composition of pathogen between the chronic airway disease patients with persistent wheezing and those without it. Method: 39 examples in the case group and 42 examples in the control group met the recruit criteria was collected. All the cases were required to provide basic information, check the routine blood test, chest X-ray or CT, pulmonary ventilation function test, sputum bacteriology, detection of atypical pathogens in blood bacteriology examination, fungal culture. Result: In the case group the ratio of positive sputum culture of fungi was 76.9%, the ratio of positive sputum culture of bacteria was 35.9%, the culture of fungi include 21 monilia and 10 aspergillus,;while in the control case the ratio of positive sputum culture of fungi was 26.2%, the ratio of positive sputum culture of bacteria was 33.3%, the 11 positive sputum culture of fungi were all monilia. Conclusion: The composition of etiology in patients with chronic airway disease in the persistent wheezing was mainly fungi, partly with bacteria. The risk factors of these patients in the persistent wheezing probably is positive sputum culture of fungi. Perhaps aspergillus is the mainly type of fungi which can cause persistent wheezing in these patients.
