中外健康文摘
中外健康文摘
중외건강문적
WORLD HEALTH DIGEST
2013年
8期
37-39
,共3页
兔%椎体骨折%MRI成像%外伤时间
兔%椎體骨摺%MRI成像%外傷時間
토%추체골절%MRI성상%외상시간
Rabbit%vertebra fracture%MRI image%injury time
目的通过比较人类椎体骨折与兔椎体骨折愈合过程中各时间段内MRI表现的相似点对照动物模型相同时间段的病理变化，从而利用MRI成像技术对人椎体骨折时间进行判定。方法1)回顾分析外伤性椎体压缩骨折68例，按照椎体骨折后MRI检查时间分为7组，分析椎体骨折时间与骨髓信号的改变。2)同年龄相近体重的雌性成年健康青紫兰兔14只，随机分为7组，每组2只。麻醉后在无菌条件下，行兔椎体基础MRI检查，按时间段行MRI及病理学观察。通过人类椎体骨折各时间段骨髓MRI信号改变，并结合病理变化进行对照研究。结果人椎体骨折在骨折区骨髓信号变化分为：水肿型、不均匀型、复原型及脂肪型，兔较人椎体愈合要快。表现为水肿型、不均匀型、复原型。根据MRI信号改变，人椎体骨折与动物椎体骨折在人类椎体骨折30天与兔椎体骨折2天的信号变化相似，呈长T1WI、长T2WI信号，即I型（水肿型）；椎体骨折30-90天与兔1-6周骨髓信号变化近似，信号分布不均，呈点片状边界清，即II型（不均匀型）；椎体骨折90-120天与兔8周骨髓信号近似，椎体信号与邻近骨髓相似，即III型（脂肪型）；但人椎体骨折愈合过程T=120天时出现脂肪型，即MRI下呈短T1长T2信号，动物则无。结论 MRI可通过对椎体骨折后骨髓信号改变的分析评判椎体骨折愈合程度。
目的通過比較人類椎體骨摺與兔椎體骨摺愈閤過程中各時間段內MRI錶現的相似點對照動物模型相同時間段的病理變化，從而利用MRI成像技術對人椎體骨摺時間進行判定。方法1)迴顧分析外傷性椎體壓縮骨摺68例，按照椎體骨摺後MRI檢查時間分為7組，分析椎體骨摺時間與骨髓信號的改變。2)同年齡相近體重的雌性成年健康青紫蘭兔14隻，隨機分為7組，每組2隻。痳醉後在無菌條件下，行兔椎體基礎MRI檢查，按時間段行MRI及病理學觀察。通過人類椎體骨摺各時間段骨髓MRI信號改變，併結閤病理變化進行對照研究。結果人椎體骨摺在骨摺區骨髓信號變化分為：水腫型、不均勻型、複原型及脂肪型，兔較人椎體愈閤要快。錶現為水腫型、不均勻型、複原型。根據MRI信號改變，人椎體骨摺與動物椎體骨摺在人類椎體骨摺30天與兔椎體骨摺2天的信號變化相似，呈長T1WI、長T2WI信號，即I型（水腫型）；椎體骨摺30-90天與兔1-6週骨髓信號變化近似，信號分佈不均，呈點片狀邊界清，即II型（不均勻型）；椎體骨摺90-120天與兔8週骨髓信號近似，椎體信號與鄰近骨髓相似，即III型（脂肪型）；但人椎體骨摺愈閤過程T=120天時齣現脂肪型，即MRI下呈短T1長T2信號，動物則無。結論 MRI可通過對椎體骨摺後骨髓信號改變的分析評判椎體骨摺愈閤程度。
목적통과비교인류추체골절여토추체골절유합과정중각시간단내MRI표현적상사점대조동물모형상동시간단적병리변화，종이이용MRI성상기술대인추체골절시간진행판정。방법1)회고분석외상성추체압축골절68례，안조추체골절후MRI검사시간분위7조，분석추체골절시간여골수신호적개변。2)동년령상근체중적자성성년건강청자란토14지，수궤분위7조，매조2지。마취후재무균조건하，행토추체기출MRI검사，안시간단행MRI급병이학관찰。통과인류추체골절각시간단골수MRI신호개변，병결합병리변화진행대조연구。결과인추체골절재골절구골수신호변화분위：수종형、불균균형、복원형급지방형，토교인추체유합요쾌。표현위수종형、불균균형、복원형。근거MRI신호개변，인추체골절여동물추체골절재인류추체골절30천여토추체골절2천적신호변화상사，정장T1WI、장T2WI신호，즉I형（수종형）；추체골절30-90천여토1-6주골수신호변화근사，신호분포불균，정점편상변계청，즉II형（불균균형）；추체골절90-120천여토8주골수신호근사，추체신호여린근골수상사，즉III형（지방형）；단인추체골절유합과정T=120천시출현지방형，즉MRI하정단T1장T2신호，동물칙무。결론 MRI가통과대추체골절후골수신호개변적분석평판추체골절유합정도。
Objective: By comparing the similarities of MRI during the healing process of human vertebra fracture and rabbit vertebra fracture,and refering to the pathological change at the same period, we can apply MRI to decide the time of fracture. Method:1)Review the 68 cases of Traumatic vertebral compression fractures, and divide them into 7 groups according to the time of checking after vertebra fracture. Analyze the time of fracture and the change of Bone marrow signal.2)Divide 21 healthy adult female Chinchilla rabbit into 7groups randomly ,3rabbits in each guoup.Feed them properly,andtake pictures of Vertebra basic MRI.Make vertebral column horizontal incisions through aseptic operation make transverse through aseptic operation make transverse pliers bite of vertebral body near the intervertebral disk without cmoplete transection then suture the cut layer by layer.avoid infection.Observe the MRI and pathology periodically.Result:The changes of bone marrow signal in case of human vertical fracture are: edema,heterogenicity,recovery,and fattiness animals recover faster from vertical fracture than human in the cases of edema,heterogenicity and recovery MRI signal of human vertical fracture after 30 days resembles that of animal vertical fracture after 2 days It shows T1W1 T2W1 signal which is the type I(edema) The bone marrow signal changes of 30days-90days after vertical fracture resembles that of animal vertical fracture within 1-6weeks.it shows an uneven distribution,with a spotted and flaky border vertical fracture within 90-120days resemble that of animal's within 8 weeks,the bone marrow signal is similar as the neighboring marrows But during the healing process of human vertical fracture,fattiness will show up around T=120days that is to say,short T1 and long T2 signals can be observed,which do not exist in animal cases.Conclusion :MRI can help judge the healing process of vertebra fracture by analyzing the changes of vertebral bone marrow signal.
