CAJ | 학술논문

目的：观察乙肝肝硬化并发脾功能亢进患者行部分脾栓塞术后抗病毒治疗的疗效。方法：对160例乙肝肝硬化并发脾亢患者进行观察，按照患者部分脾栓塞术后是否进行抗病毒治疗将其分为两组，A组80例未行抗病毒治疗，B组80例行抗病毒治疗。对上述患者进行6个月的观察，包括病毒载量、肝功能检查及上消化道出血情况。结果：A组治疗第6个月的各项肝功能监测数据明显高于B组，差异具有统计学意义（P<0.05）；A组治疗3个月后乙肝病毒载量及发生再发性消化道出血的患者均明显高于B组，差异具有统计学意义（P<0.05）。结论：部分脾栓塞术后乙肝病毒载量均有升高，且肝功能无明显改善，而加强术后抗病毒治疗，可以改善肝功能，提高患者生活质量，延长生存期。
목적：관찰을간간경화병발비공능항진환자행부분비전새술후항병독치료적료효。방법：대160례을간간경화병발비항환자진행관찰，안조환자부분비전새술후시부진행항병독치료장기분위량조，A조80례미행항병독치료，B조80례행항병독치료。대상술환자진행6개월적관찰，포괄병독재량、간공능검사급상소화도출혈정황。결과：A조치료제6개월적각항간공능감측수거명현고우B조，차이구유통계학의의（P<0.05）；A조치료3개월후을간병독재량급발생재발성소화도출혈적환자균명현고우B조，차이구유통계학의의（P<0.05）。결론：부분비전새술후을간병독재량균유승고，차간공능무명현개선，이가강술후항병독치료，가이개선간공능，제고환자생활질량，연장생존기。
Objective:To observe hepatitis b cirrhosis patients complicated with the splenic function after partial splenic embolization postoperative antiviral of treatment the curative effect. Method:160 cases with hepatitis B liver cirrhosis complicated with hypersplenism patients according to whether on postoperative antiviral treatment was divided into two groups,80 cases of group A was no antiviral treatment group,80 cases of group B antiviral treatment group. Observed the patients’ viral load,liver function and upper gastrointestinal bleeding for six months. Result:A group treatment 6 months was significantly higher than group B and differences in the had statistically significant(P<0.05);Postoperative 3 months after the group A patients with recurrent gastrointestinal bleeding,and hepatitis B viral load were significantly higher than that of group B,differences had statistically significant(P<0.05). Conclusion:After partial splenic embolization of hepatitis b viral load are higher,and no obvious improve liver function,and strengthen the postoperative antiviral treatment,can improve the liver function,and improve patients quality of life and prolong the survival period.