医学美学美容（中旬刊）
醫學美學美容（中旬刊）
의학미학미용（중순간）
MEDICAL AESTHETICS AND COSMETOLOGY
2013年
9期
15-17
,共3页
谢顺珍%邓列华(通讯作者)%胡云峰%赵刚%刘赛君%孙乐栋%罗育武%李克俭%徐瑾%李诗娜%陈国瑞
謝順珍%鄧列華(通訊作者)%鬍雲峰%趙剛%劉賽君%孫樂棟%囉育武%李剋儉%徐瑾%李詩娜%陳國瑞
사순진%산렬화(통신작자)%호운봉%조강%류새군%손악동%라육무%리극검%서근%리시나%진국서
伊曲康唑胶囊%2％ 酮康唑乳膏%足癣
伊麯康唑膠囊%2％ 酮康唑乳膏%足癬
이곡강서효낭%2％ 동강서유고%족선
Itraconazole Capsules%2％ ketoconazole cream%Tinea pedis
目的：观察伊曲康唑胶囊联合2％酮康唑乳膏治疗足癣的近期临床疗效。方法：将94例足癣患者随机分为治疗组（口服伊曲康唑胶囊200 mg 每天1次，联合外用2％酮康唑乳膏每天2次）；对照组（单纯外用2％酮康唑乳膏每天2次）；两组各47例，用药疗程均为4周。观察两组患者用药后2周、4周及停药后2周的临床疗效和真菌学疗效及不良反应。结果：用药后2周治疗组和对照组总有效率分别为25．5％、17．0％，真菌清除率分别为25．5％、17．0％，两组比较差异无统计学意义（P＞0．05）；用药后4周治疗组和对照组总有效率分别为61．7％、40．4％，真菌清除率分别为68．1％、44．7％，两组比较差异有统计学意义（P＜0．05）；停药后2周治疗组和对照组总有效率分别为80．9、55．3％，真菌清除率分别为89．4％、59．6％，两组比较差异有统计学意义（P＜0．05）。两组患者用药后均无严重不良反应发生。结论：口服伊曲康唑胶囊联合外用2％酮康唑乳膏比单纯外用2％酮康唑乳膏治疗足癣近期临床疗效及真菌学疗效好，且副作用少，是临床治疗足癣疗效较好的方法之一。
目的：觀察伊麯康唑膠囊聯閤2％酮康唑乳膏治療足癬的近期臨床療效。方法：將94例足癬患者隨機分為治療組（口服伊麯康唑膠囊200 mg 每天1次，聯閤外用2％酮康唑乳膏每天2次）；對照組（單純外用2％酮康唑乳膏每天2次）；兩組各47例，用藥療程均為4週。觀察兩組患者用藥後2週、4週及停藥後2週的臨床療效和真菌學療效及不良反應。結果：用藥後2週治療組和對照組總有效率分彆為25．5％、17．0％，真菌清除率分彆為25．5％、17．0％，兩組比較差異無統計學意義（P＞0．05）；用藥後4週治療組和對照組總有效率分彆為61．7％、40．4％，真菌清除率分彆為68．1％、44．7％，兩組比較差異有統計學意義（P＜0．05）；停藥後2週治療組和對照組總有效率分彆為80．9、55．3％，真菌清除率分彆為89．4％、59．6％，兩組比較差異有統計學意義（P＜0．05）。兩組患者用藥後均無嚴重不良反應髮生。結論：口服伊麯康唑膠囊聯閤外用2％酮康唑乳膏比單純外用2％酮康唑乳膏治療足癬近期臨床療效及真菌學療效好，且副作用少，是臨床治療足癬療效較好的方法之一。
목적：관찰이곡강서효낭연합2％동강서유고치료족선적근기림상료효。방법：장94례족선환자수궤분위치료조（구복이곡강서효낭200 mg 매천1차，연합외용2％동강서유고매천2차）；대조조（단순외용2％동강서유고매천2차）；량조각47례，용약료정균위4주。관찰량조환자용약후2주、4주급정약후2주적림상료효화진균학료효급불량반응。결과：용약후2주치료조화대조조총유효솔분별위25．5％、17．0％，진균청제솔분별위25．5％、17．0％，량조비교차이무통계학의의（P＞0．05）；용약후4주치료조화대조조총유효솔분별위61．7％、40．4％，진균청제솔분별위68．1％、44．7％，량조비교차이유통계학의의（P＜0．05）；정약후2주치료조화대조조총유효솔분별위80．9、55．3％，진균청제솔분별위89．4％、59．6％，량조비교차이유통계학의의（P＜0．05）。량조환자용약후균무엄중불량반응발생。결론：구복이곡강서효낭연합외용2％동강서유고비단순외용2％동강서유고치료족선근기림상료효급진균학료효호，차부작용소，시림상치료족선료효교호적방법지일。
Objective :To observe the efficacy of oral Itraconazole Capsules combined with external use 2% ketoconazole cream treating tinea pedis . Methods :94 patients with tinea pedis ,were randomly divided into treatment group and control group .Treatment group oral Itraconazole Capsules combined with external use 2% ketoconazole cream treating 47 patients with tinea pedis ,the total course of 4 weeks .Control group external use 2%ketoconazole cream treating 47 patients with tinea pedis ,the total course of 4 weeks .Observe two groups of patients with drug use 2 weeks、4 weeks and after discontinuation 2 weeks of clinical curative effect and mycology curative effect and adverse reactions .Results:Two groups of patients with drug use 2 weeks the effective rate were 25 .5% and 17 .0% respectively ,the fungus eradication rate were 34 .0% and 23 .4% respectively .There was no statistically significant difference comparing the two groups (P﹥0 .05) .Two groups of patients with drug use 4 weeks the effective rate were 61 . 7% and 40 .4% respectively ,the fungus eradication rate were 72 .3% and 46 .8% respectively .Comparative differences between the two groups have statistical significance (P<0 .05) .Two groups patients after discontinuation 2 weeks of the effective rate were 80 .9% and 55 .3% respectively ,the fun-gus eradication rate were 91 .5% and 61 .7% respectively .Comparative differences between the two groups have statistical significance (P<0 .05) .Two groups of patients with no serious adverse reaction after taking this medicine .Conclusion :Oral Itraconazole Capsules combined with external use 2%ketoconazole cream in the treatment of tinea pedis clinical curative effect and mycology curative effect is good ,Side effects are less .
