中国妇幼健康研究
中國婦幼健康研究
중국부유건강연구
CHINESE JOURNAL OF MATERNAL AND CHILD HEALTH RESEARCH
2014年
2期
244-245,246
,共3页
吴芬英%李媛%孟杨南%田徐琴%李莎
吳芬英%李媛%孟楊南%田徐琴%李莎
오분영%리원%맹양남%전서금%리사
妊娠期糖尿病%糖筛查试验%葡萄糖耐量试验%不良反应%妊娠结局
妊娠期糖尿病%糖篩查試驗%葡萄糖耐量試驗%不良反應%妊娠結跼
임신기당뇨병%당사사시험%포도당내량시험%불량반응%임신결국
gestational diabetes mellitus (GDM)%glucose screening test (GST)%oral g1ucose tolerance test (OGTT)%adverse reactions%pregnancy outcomes
目的：探讨孕妇在不同妊娠期糖尿病筛查方法及妊娠结局。方法对600例孕妇分组进行教科书建议的50 g糖筛查试验（GST）和采用国际妊娠与糖尿病研究组织（IADPSG）诊断标准的75g葡萄糖耐量试验（OGTT），对试验阴性者的不良反应、剖宫产率、胎儿窘迫、胎膜早破、妊娠期高血压疾病、羊水过多、产后出血的发生率及新生儿窒息、畸形、早产儿、巨大儿的发生率等资料进行分析。结果 GST组阴性为81．67％，OGTT组阴性为79．00％。两组孕妇剖宫产率、胎儿窘迫、胎膜早破、妊娠期高血压疾病、羊水过多、产后出血的发生率及新生儿窒息、畸形、早产儿、巨大儿的发生率比较差异均不显著，而OGTT组服糖后不良反应大于GST组，（χ2＝7．0015，P＜0．05）。结论如果以糖耐量异常为干预点，则两种诊断标准阴性者围产期结局无显著性差异；但采用IADPSG诊断标准进行OGTT试验会增加孕妇服糖的不良反应，依从性低，且增加了医院检验科的工作量，在我国县镇医院，推广需谨慎。
目的：探討孕婦在不同妊娠期糖尿病篩查方法及妊娠結跼。方法對600例孕婦分組進行教科書建議的50 g糖篩查試驗（GST）和採用國際妊娠與糖尿病研究組織（IADPSG）診斷標準的75g葡萄糖耐量試驗（OGTT），對試驗陰性者的不良反應、剖宮產率、胎兒窘迫、胎膜早破、妊娠期高血壓疾病、羊水過多、產後齣血的髮生率及新生兒窒息、畸形、早產兒、巨大兒的髮生率等資料進行分析。結果 GST組陰性為81．67％，OGTT組陰性為79．00％。兩組孕婦剖宮產率、胎兒窘迫、胎膜早破、妊娠期高血壓疾病、羊水過多、產後齣血的髮生率及新生兒窒息、畸形、早產兒、巨大兒的髮生率比較差異均不顯著，而OGTT組服糖後不良反應大于GST組，（χ2＝7．0015，P＜0．05）。結論如果以糖耐量異常為榦預點，則兩種診斷標準陰性者圍產期結跼無顯著性差異；但採用IADPSG診斷標準進行OGTT試驗會增加孕婦服糖的不良反應，依從性低，且增加瞭醫院檢驗科的工作量，在我國縣鎮醫院，推廣需謹慎。
목적：탐토잉부재불동임신기당뇨병사사방법급임신결국。방법대600례잉부분조진행교과서건의적50 g당사사시험（GST）화채용국제임신여당뇨병연구조직（IADPSG）진단표준적75g포도당내량시험（OGTT），대시험음성자적불량반응、부궁산솔、태인군박、태막조파、임신기고혈압질병、양수과다、산후출혈적발생솔급신생인질식、기형、조산인、거대인적발생솔등자료진행분석。결과 GST조음성위81．67％，OGTT조음성위79．00％。량조잉부부궁산솔、태인군박、태막조파、임신기고혈압질병、양수과다、산후출혈적발생솔급신생인질식、기형、조산인、거대인적발생솔비교차이균불현저，이OGTT조복당후불량반응대우GST조，（χ2＝7．0015，P＜0．05）。결론여과이당내량이상위간예점，칙량충진단표준음성자위산기결국무현저성차이；단채용IADPSG진단표준진행OGTT시험회증가잉부복당적불량반응，의종성저，차증가료의원검험과적공작량，재아국현진의원，추엄수근신。
Objective To investigate different screening methods for gestational diabetes mellitus ( GDM ) and pregnancy outcomes . Methods Totally 600 pregnant women were divided into two groups , which separately tested by 50g glucose screening test (GST group) and 75g oral glucose tolerance test by International Association of Diabetes and Pregnancy Study Groups (IADPSG) (OGTT group).The adverse reactions , cesarean section rate , fetal distress, premature rupture of membranes , hypertensive disorders in pregnancy , polyhydramnios , incidence of postpartum hemorrhage , incidence of neonatal asphyxia , malformation , premature infant and macrosomia of pregnant women with negative results were analyzed .Results The negative rate in GST group was 81.67%, but in OGTT group it was 79.00%.There was no obvious difference in the incidence rate between two groups .The pregnant women showed more adverse reactions in OGTT group than in GST group (χ2 =7.0015, P<0.05).Conclusion If impaired glucose tolerance (IGT) is selected as intervention point , women with negative results show no obvious differences by two diagnostic criteria .Pregnant women will show more adverse reactions after taking glucose if tested by OGTT and diagnosed by IADPSG , which also increases hospital laboratory work .So we should be prudent in populating this way in county hospitals in China .
