CAJ | 학술논문

目的探讨经颅多普勒超声监测脑血流动力学参数对早期发现多发性脑梗塞患者认知障碍的应用价值。方法对156例维吾尔族多发性脑梗塞（MI）患者进行经颅多普勒超声（TCD）、简易智力状况检查量表（MMSE）动态监测，每3个月监测1次，共24个月，对结果进行统计分析。结果多发性脑梗塞性痴呆（MID）发病率为25．0％（39/156），其中23例发生于随访的9个月后，占58．9％；随访中出现痴呆的患者的平均血流速度（Vm）降低，而搏动指数（PI）增加。与单纯 MI组相比，两组 Vm从9个月开始即显示出明显的差异，较 MID的发生高峰提前约3个月。结论用TCD动态监测维吾尔族MI患者的脑血流动力学参数对早期发现多发性脑梗塞患者认知障碍有重要价值。
목적탐토경로다보륵초성감측뇌혈류동역학삼수대조기발현다발성뇌경새환자인지장애적응용개치。방법대156례유오이족다발성뇌경새（MI）환자진행경로다보륵초성（TCD）、간역지력상황검사량표（MMSE）동태감측，매3개월감측1차，공24개월，대결과진행통계분석。결과다발성뇌경새성치태（MID）발병솔위25．0％（39/156），기중23례발생우수방적9개월후，점58．9％；수방중출현치태적환자적평균혈류속도（Vm）강저，이박동지수（PI）증가。여단순 MI조상비，량조 Vm종9개월개시즉현시출명현적차이，교 MID적발생고봉제전약3개월。결론용TCD동태감측유오이족MI환자적뇌혈류동역학삼수대조기발현다발성뇌경새환자인지장애유중요개치。
Objective To evaluate the value of transcranial Dopper(TCD)in screening multiple cerebral in-farction patients with cognitive impairment.Methods 1 5 6 Uygur Patients with MI were determined regu-larly every 3 months with TCD and MMSE for 24 months.Results Among 156 patients with MI,the inci-dence of multiple infarct dementia(MID)was 25.0%(39/156),23 cases occurred during the period of 9 months,accounting for 58.9%(23/39);Among patients with and without dementia,significant difference was found in Vm and PI.Compared with the simple MI group,significant Vm appeared in the 9th month. Conclusion It is valuable to determine Vm and RI regularly for early diagnosis of cognitive impairment of patients with muti-infarction.