中华劳动卫生职业病杂志
中華勞動衛生職業病雜誌
중화노동위생직업병잡지
CHINESE JOURNAL OF INDUSTRIAL HYGIENE AND OCCUPATIONAL DISEASES
2014年
2期
83-86
,共4页
吴辉%姜开友%谷桂珍%吴艳延%余善法
吳輝%薑開友%穀桂珍%吳豔延%餘善法
오휘%강개우%곡계진%오염연%여선법
职业紧张%激素代谢物%尿液
職業緊張%激素代謝物%尿液
직업긴장%격소대사물%뇨액
Occupational stress%Hormone metabolites%Urine
目的 探讨尿液中激素代谢物17-羟皮质类固醇(17-OHCS)、17-酮皮质类固醇(17-KS)、香草扁桃酸(VMA)及高香草酸(HVA)作为职业应激评价指标的可能性,为职业应激的识别与评价提供科学依据.方法 以方便抽样与整群抽样方法,抽取某市公安局某派出所的225名在职民警为研究对象.使用问卷调查其人口统计学特征和职业应激相关因素.采用酶联免疫吸附试验和高效液相色谱-荧光检测法对尿液中17-OHCS、17-KS、VMA和HVA浓度进行检测.应用SPSS 12.0软件对数据进行t检验、协方差分析和多因素非条件logistic回归等统计学分析.结果 工作控制和同事支持高评分组的17-OHCS水平低于低评分组,负性情绪高评分组的17-OHCS水平高于低评分组,差异均有统计学意义(P＜0.05)；工作保障高评分组的17-KS水平低于低评分组,差异有统计学意义(P＜0.05)；同事支持高评分组的VMA水平低于低评分组,非工作压力的高评分组的VMA水平高于低评分组,差异均有统计学意义(P＜0.05)；应付策略高评分组的HVA水平低于低评分组,差异有统计学意义(P＜0.05).logistic回归分析发现,饮酒者的17-OHCS水平升高风险是不饮酒者的0.385倍,工作控制和尊重高评分组的17-OHCS水平升高风险分别是其低评分组的0.353、0.352倍,户籍警与刑警的17-OHCS水平升高风险分别是交警的3.409、3.600倍,内在投入、自尊感和每日紧张感高评分组的17-OHCS水平升高风险分别是其低评分组的3.391、2.439、2.584倍；刑警的17-KS水平升高风险是交警的2.949倍,工作控制和工作保障高评分组的17-KS水平升高风险分别是其低评分组的0.387、0.356倍；负性情绪高评分组的VMA水平升高风险是低评分组的2.643倍.结论 尿液中17-OHCS、17-KS和VMA是职业应激客观评价的潜在指标.
目的 探討尿液中激素代謝物17-羥皮質類固醇(17-OHCS)、17-酮皮質類固醇(17-KS)、香草扁桃痠(VMA)及高香草痠(HVA)作為職業應激評價指標的可能性,為職業應激的識彆與評價提供科學依據.方法 以方便抽樣與整群抽樣方法,抽取某市公安跼某派齣所的225名在職民警為研究對象.使用問捲調查其人口統計學特徵和職業應激相關因素.採用酶聯免疫吸附試驗和高效液相色譜-熒光檢測法對尿液中17-OHCS、17-KS、VMA和HVA濃度進行檢測.應用SPSS 12.0軟件對數據進行t檢驗、協方差分析和多因素非條件logistic迴歸等統計學分析.結果 工作控製和同事支持高評分組的17-OHCS水平低于低評分組,負性情緒高評分組的17-OHCS水平高于低評分組,差異均有統計學意義(P＜0.05)；工作保障高評分組的17-KS水平低于低評分組,差異有統計學意義(P＜0.05)；同事支持高評分組的VMA水平低于低評分組,非工作壓力的高評分組的VMA水平高于低評分組,差異均有統計學意義(P＜0.05)；應付策略高評分組的HVA水平低于低評分組,差異有統計學意義(P＜0.05).logistic迴歸分析髮現,飲酒者的17-OHCS水平升高風險是不飲酒者的0.385倍,工作控製和尊重高評分組的17-OHCS水平升高風險分彆是其低評分組的0.353、0.352倍,戶籍警與刑警的17-OHCS水平升高風險分彆是交警的3.409、3.600倍,內在投入、自尊感和每日緊張感高評分組的17-OHCS水平升高風險分彆是其低評分組的3.391、2.439、2.584倍；刑警的17-KS水平升高風險是交警的2.949倍,工作控製和工作保障高評分組的17-KS水平升高風險分彆是其低評分組的0.387、0.356倍；負性情緒高評分組的VMA水平升高風險是低評分組的2.643倍.結論 尿液中17-OHCS、17-KS和VMA是職業應激客觀評價的潛在指標.
목적 탐토뇨액중격소대사물17-간피질류고순(17-OHCS)、17-동피질류고순(17-KS)、향초편도산(VMA)급고향초산(HVA)작위직업응격평개지표적가능성,위직업응격적식별여평개제공과학의거.방법 이방편추양여정군추양방법,추취모시공안국모파출소적225명재직민경위연구대상.사용문권조사기인구통계학특정화직업응격상관인소.채용매련면역흡부시험화고효액상색보-형광검측법대뇨액중17-OHCS、17-KS、VMA화HVA농도진행검측.응용SPSS 12.0연건대수거진행t검험、협방차분석화다인소비조건logistic회귀등통계학분석.결과 공작공제화동사지지고평분조적17-OHCS수평저우저평분조,부성정서고평분조적17-OHCS수평고우저평분조,차이균유통계학의의(P＜0.05)；공작보장고평분조적17-KS수평저우저평분조,차이유통계학의의(P＜0.05)；동사지지고평분조적VMA수평저우저평분조,비공작압력적고평분조적VMA수평고우저평분조,차이균유통계학의의(P＜0.05)；응부책략고평분조적HVA수평저우저평분조,차이유통계학의의(P＜0.05).logistic회귀분석발현,음주자적17-OHCS수평승고풍험시불음주자적0.385배,공작공제화존중고평분조적17-OHCS수평승고풍험분별시기저평분조적0.353、0.352배,호적경여형경적17-OHCS수평승고풍험분별시교경적3.409、3.600배,내재투입、자존감화매일긴장감고평분조적17-OHCS수평승고풍험분별시기저평분조적3.391、2.439、2.584배；형경적17-KS수평승고풍험시교경적2.949배,공작공제화공작보장고평분조적17-KS수평승고풍험분별시기저평분조적0.387、0.356배；부성정서고평분조적VMA수평승고풍험시저평분조적2.643배.결론 뇨액중17-OHCS、17-KS화VMA시직업응격객관평개적잠재지표.
Objective To explore the possibility for 17-OHCS,17-KS,VMA and HVA in urine as indicators of occupational stress identification and evaluation.Methods 225 polices were investigated by using convenience sampling and cluster sampling methods,occupational stressors,strains,buffer factors and individual factors were measured by questionnaires.The urine 17-OHCS,17-KS,VMA and HVA level was tested by ELISA and high performance liquid chromatography method respectively.Results The urine 17-OHCS level of the groups with high coworker support and job control scores was lower than that of the groups with low score groups (P＜O.05),the urine 17-OHCS level of the group with high negative affectivity score was higher than that of the group with low score group (P＜0.05).The urine 17-KS level of the group with high job security score was lower than that of the counterparts (P＜0.05).The urine VMA level of the group with high coworker support score was lower than that of the counterparts (P＜0.05).The urine HVA level of the group with high coping strategy score was lower than that of counterparts (P＜0.05).Logistic regression analysis reveled that the job control and respect were the protective factors of urine 17-OHCS level increase (OR=0.353 and 0.352 respectively),but over-commitment,self-esteem and daily hassles were the risk factors of urine 17-OHCS with level increase (OR=3.391,2.439,and 2.584 respectively).The risk of urine 17-KS level increase for the groups high job control and job security scores were respectively 0.387,0.356 times than that of the counterparts,the risk of urine VMA level increase for the group with high negative affectivitv score was 2.643 times than that of the counterparts.Conclusion The urine 17-OHCS,17-KS and VMA level were potential indicators for occupational stress evaluation.
