中国医药科学
中國醫藥科學
중국의약과학
CHINA MEDICINE AND PHARMACY
2013年
19期
93-94
,共2页
左氧氟沙星%抗结核化疗%初治涂阳肺结核
左氧氟沙星%抗結覈化療%初治塗暘肺結覈
좌양불사성%항결핵화료%초치도양폐결핵
Levofloxacin%Antituberculous chemotherapy%Initial smear-positive pulmonary tuberculosis
目的 探讨初治涂阳肺结核采用左氧氟沙星分散片联合抗结核化疗方案治疗的临床实践效果。 方法 收取2011 年1 月~2013 年1 月在我院治疗的初治涂阳肺结核100 例，随机分为实验组和对照组，两组各50 例。实验组采用2HRZE/4HR 治疗方案加入左氧氟沙星分散片，对照组采用2HRZE/4HR 治疗方案，整个疗程为6 个月，统计用药2、4、6 个月以后检测患者的痰菌的阴转率、病灶吸收率，并密切观察患者症状的改善情况、ADR 情况，分析两种治疗方法的临床治疗效果。 结果 痰菌的阴转率实验组优于对照组，病灶吸收率实验组优于对照组，两组间差异具有统计学意义（P ＜ 0.05）。 结论 初治涂阳肺结核采用左氧氟沙星分散片联合抗结核化疗方案临床效果显著，具有推广应用价值。
目的 探討初治塗暘肺結覈採用左氧氟沙星分散片聯閤抗結覈化療方案治療的臨床實踐效果。 方法 收取2011 年1 月~2013 年1 月在我院治療的初治塗暘肺結覈100 例，隨機分為實驗組和對照組，兩組各50 例。實驗組採用2HRZE/4HR 治療方案加入左氧氟沙星分散片，對照組採用2HRZE/4HR 治療方案，整箇療程為6 箇月，統計用藥2、4、6 箇月以後檢測患者的痰菌的陰轉率、病竈吸收率，併密切觀察患者癥狀的改善情況、ADR 情況，分析兩種治療方法的臨床治療效果。 結果 痰菌的陰轉率實驗組優于對照組，病竈吸收率實驗組優于對照組，兩組間差異具有統計學意義（P ＜ 0.05）。 結論 初治塗暘肺結覈採用左氧氟沙星分散片聯閤抗結覈化療方案臨床效果顯著，具有推廣應用價值。
목적 탐토초치도양폐결핵채용좌양불사성분산편연합항결핵화료방안치료적림상실천효과。 방법 수취2011 년1 월~2013 년1 월재아원치료적초치도양폐결핵100 례，수궤분위실험조화대조조，량조각50 례。실험조채용2HRZE/4HR 치료방안가입좌양불사성분산편，대조조채용2HRZE/4HR 치료방안，정개료정위6 개월，통계용약2、4、6 개월이후검측환자적담균적음전솔、병조흡수솔，병밀절관찰환자증상적개선정황、ADR 정황，분석량충치료방법적림상치료효과。 결과 담균적음전솔실험조우우대조조，병조흡수솔실험조우우대조조，량조간차이구유통계학의의（P ＜ 0.05）。 결론 초치도양폐결핵채용좌양불사성분산편연합항결핵화료방안림상효과현저，구유추엄응용개치。
Objective To study the clinical practice effect of initial smear-positive pulmonary tuberculosis with levofloxacin injection combined with chemotherapy in the treatment of tuberculosis. Methods 100 cases of patients with initial smear-positive pulmonary tuberculosis were selected from June 2012 to June 2013 in our hospital and were randomly divided into experimental group and control group, two groups of 50 cases. The experimental group was treated with 2HRZE/4HR scheme of adding levofloxacin dispersible tablets, the control group was treated with 2HRZE/4HR scheme, the whole course of treatment for 6 months, then gathered the sputum negative conversion rate of detection of the patient, the focus absorption rate, the improvement of the patients' symptoms, ADR and closely observe the patientsymptom after 2, 4, 6 monthes, and analyzed the clinical curative effect of the two treatment methods. Results The sputum negative conversion rate of the experimental group was significantly better than the control group, the focus absorption rate of experimental group was better than the control group, the difference between the two groups was statistically significant (P < 0.05). Conclusion The treatment of initial smear-positive pulmonary tuberculosis with levofloxacin combined with antituberculosis chemotherapy clinical effect is remarkable, and has popularization and application value.
