CAJ | 학술논문

目的：探讨中药活化克岩酊的作用机理，为临床用药提供理论依据。方法：分别取小鼠48只和100只，随机分成4组，每组分别为12只和25只。模型对照组外用同体积的生理盐水，阳性对照组外用正红花油，实验高浓度组和低浓度组外用100%和60%的中药活化克岩酊。连续给药6～8天，每天1次。小鼠尾静脉注射垂体后叶素，使小动脉血流速度减慢；将各组小鼠固定筒座，鼠尾置于光电控制的光孔中间，测定小鼠甩尾时间。结果：中药活化克岩酊能加快小鼠耳部小动脉的血流速度；同时能显著抑制光电所致的疼痛。结论：中药活化克岩酊具有改善微血环与镇痛的作用。
목적：탐토중약활화극암정적작용궤리，위림상용약제공이론의거。방법：분별취소서48지화100지，수궤분성4조，매조분별위12지화25지。모형대조조외용동체적적생리염수，양성대조조외용정홍화유，실험고농도조화저농도조외용100%화60%적중약활화극암정。련속급약6～8천，매천1차。소서미정맥주사수체후협소，사소동맥혈류속도감만；장각조소서고정통좌，서미치우광전공제적광공중간，측정소서솔미시간。결과：중약활화극암정능가쾌소서이부소동맥적혈류속도；동시능현저억제광전소치적동통。결론：중약활화극암정구유개선미혈배여진통적작용。
Object:Explore the action mechanism of the activated KeYan Ding to provide the experimental data for clinical treatment. Methods:The first group have 48 mice, were divided into 4 groups randomly, 12 in every group.and the second group have 100 mice, were divided into 4 groups randomly too, 25 in every group. the model group were given saline for external application; the positive control group were given safflower oil for external application; the experiment of high concentration and low concentration group were given activated KeYan Ding 100%and 60%respectively for external application. were given for 6~8 days,one time a day. injected pituitrin to the caudal vein of mice to slow down the speed of the blood in arteriole;The mice in each group were fixed inside the cylinder base, tail in the middle of photoelectric control light hole, determinate tail time of the mice.Results:The activated KeYan Ding could accelerate blood flow velocity of the mice ear arteriolar; can obviously inhibit the pain induced by photoelectric moreover .Conclusion:The herbal activated KeYan Ding have the function to improve microcirculation and analgesia.