中国保健营养(中旬刊)
中國保健營養(中旬刊)
중국보건영양(중순간)
China Hwalth Care & nutrition
2014年
5期
2714-2715
,共2页
范新迎%施旭新%夏平%万美燕%邹作君
範新迎%施旭新%夏平%萬美燕%鄒作君
범신영%시욱신%하평%만미연%추작군
早期肾脏病人%尿酸排泄分数%钙排泄分数%健康老年人
早期腎髒病人%尿痠排洩分數%鈣排洩分數%健康老年人
조기신장병인%뇨산배설분수%개배설분수%건강노년인
Early kidney patients%Uric acid excretion score%Calcium excretion score%The healthy elderly
目的:研究健康老年人生理性肾功能减退与相应eGFR水平的早期CKD患者尿酸、钙、镁、磷、钾、尿酸等物质排泄情况的差异。方法:选取2012年-2013年山东省青岛市立医院肾内科以糖尿病为原发病的CKD早期(1-2期)病人(CKD早期病人),正常老年组选取查体后筛选无肾脏病的70岁以上老年人,分别检测空腹血清中肌酐、尿酸、钙、镁、磷、钾,晨尿中肌酐、尿酸、钙、镁、磷、钾含量,计算eGFR及各物质排泄分数(FE),进行对比。结果:CKD早期病人较健康老年人血肌酐有显著差异(p<0.01),eGFR相当,无统计学差异(P>0.05)。血清尿酸,血清镁,血清磷,血清钾较健康老年人有显著性差异(P<0.05,p<0.05,p<0.01,p<0.01),FECa,FEUA无明显差异。结论:70岁以上健康老年人与以糖尿病为原发病的早期CKD病人肾小球滤过率相当,但物质排泄存在差异,两者为不同的病理生理状态,临床上需区别对待。
目的:研究健康老年人生理性腎功能減退與相應eGFR水平的早期CKD患者尿痠、鈣、鎂、燐、鉀、尿痠等物質排洩情況的差異。方法:選取2012年-2013年山東省青島市立醫院腎內科以糖尿病為原髮病的CKD早期(1-2期)病人(CKD早期病人),正常老年組選取查體後篩選無腎髒病的70歲以上老年人,分彆檢測空腹血清中肌酐、尿痠、鈣、鎂、燐、鉀,晨尿中肌酐、尿痠、鈣、鎂、燐、鉀含量,計算eGFR及各物質排洩分數(FE),進行對比。結果:CKD早期病人較健康老年人血肌酐有顯著差異(p<0.01),eGFR相噹,無統計學差異(P>0.05)。血清尿痠,血清鎂,血清燐,血清鉀較健康老年人有顯著性差異(P<0.05,p<0.05,p<0.01,p<0.01),FECa,FEUA無明顯差異。結論:70歲以上健康老年人與以糖尿病為原髮病的早期CKD病人腎小毬濾過率相噹,但物質排洩存在差異,兩者為不同的病理生理狀態,臨床上需區彆對待。
목적:연구건강노년인생이성신공능감퇴여상응eGFR수평적조기CKD환자뇨산、개、미、린、갑、뇨산등물질배설정황적차이。방법:선취2012년-2013년산동성청도시립의원신내과이당뇨병위원발병적CKD조기(1-2기)병인(CKD조기병인),정상노년조선취사체후사선무신장병적70세이상노년인,분별검측공복혈청중기항、뇨산、개、미、린、갑,신뇨중기항、뇨산、개、미、린、갑함량,계산eGFR급각물질배설분수(FE),진행대비。결과:CKD조기병인교건강노년인혈기항유현저차이(p<0.01),eGFR상당,무통계학차이(P>0.05)。혈청뇨산,혈청미,혈청린,혈청갑교건강노년인유현저성차이(P<0.05,p<0.05,p<0.01,p<0.01),FECa,FEUA무명현차이。결론:70세이상건강노년인여이당뇨병위원발병적조기CKD병인신소구려과솔상당,단물질배설존재차이,량자위불동적병리생리상태,림상상수구별대대。
objective:to study the physiological renal impairment in the elderly health and the level of eGFR early uric acid in patients with chronic kidney disease (CKD), calcium, magnesium, phosphorus, potassium, such as uric acid excretion condition difference. Method:choose 2012-2013 in shandong province Qingdao city hospital urology department with diabetes as primary disease early chronic kidney disease (CKD) (1-2) patients early (CKD patients), after the body normal elderly group selected filter without kidney disease of the elderly over the age of 70, on an empty stomach was detected in serum creatinine, uric acid, calcium, magnesium, phosphorus, potassium, morning urine creatinine, uric acid, calcium, magnesium, phosphorus, potassium content, calculation of eGFR and each material discharge mark (FE), for comparison. Results:the patients with early chronic kidney disease (CKD) is the healthy elderly serum creatinine have significant difference (p<0.01), eGFR, no statistical difference (p>0.05). Serum uric acid, serum magnesium, phosphorus, serum potassium is healthy elderly people have significant difference (P<0.05, P<0.05, P<0.01, P<0.01), the FECa, no obvious difference was found between FEUA. Conclusion:more than 70-year-old healthy elderly people with diabetes as the primary disease of early chronic kidney disease (CKD) patients with glomerular filtration rate, but the material discharge differences, both for the different pathological physiology, clinical need.