CAJ | 학술논문

邻氯苯亚甲基丙二腈通过工业新工艺而合成，以邻氯苯甲醛和丙二腈为原料，以乙醇为溶剂，以氢氧化钠-四丁基溴化铵配制的复合催化剂为催化剂，室温反应30 min，析出物离心分离、干燥后即得到高纯度的白色晶体邻氯苯亚甲基丙二腈。此新工艺的优点：收率高，产品纯度高，结晶粒度均匀；无需用无水乙醇重结晶，工艺简单，反应、结晶和提纯同时进行；反应母液可以循环利用10次以上，并且产品的收率不会随着循环次数的增加而降低，合成工艺成本降低30%以上。
린록분아갑기병이정통과공업신공예이합성，이린록분갑철화병이정위원료，이을순위용제，이경양화납-사정기추화안배제적복합최화제위최화제，실온반응30 min，석출물리심분리、간조후즉득도고순도적백색정체린록분아갑기병이정。차신공예적우점：수솔고，산품순도고，결정립도균균；무수용무수을순중결정，공예간단，반응、결정화제순동시진행；반응모액가이순배이용10차이상，병차산품적수솔불회수착순배차수적증가이강저，합성공예성본강저30%이상。
O-Chlorobenzylidenemalononitrile(CS) is synthesized via the new industrial synthesis process in the presence of sodium hydroxide/tetrabutylammonium bromide prepared composite catalyst as catalyst,using o-chlorobenzaldehyde and malononitrile as raw material and absolute ethyl alcohol as solvent. After the reaction at room temperature for 30 minutes,precipitation is separated and dried to obtain high purity white crystal CS. This new process has many advantages,such as high yield,high product purity,crystals with uniform size;without the use of anhydrous alcohol recrystallization;simple process,reaction,crystallization and purification at the same time. The reaction mother liquid can be recycled more than ten times,and the yield of the product is not reduced with cycle number increases. The production cost reduces more than 30%than the existing synthetic process.