CAJ | 학술논문

目的：：对慢性胃炎儿童患者13C-尿素呼气试验(13C-UBT)和胃黏膜活体组织检查(活检)Hp两种检测方法进行比较分析。方法：选取我院收治的慢性胃炎儿童患者46例,分别进行13C-尿素呼气试验检测和胃黏膜活检Hp检测,并以胃黏膜活检Hp检测结果为标准,比较13C-UBT对幽门螺旋杆菌检出的准确度、特异性和敏感度；并对检测出Hp阳性患者采用质子泵抑制剂(PPI)进行治疗,观察其临床疗效。结果：胃黏膜活检Hp检测结果显示,13C-UBT的准确度、特异性和敏感度分别为97.83%、92.86%和100%,且对Hp阳性患者采用PPI三联疗法治疗的转阴率要显著优于采用单纯PPI和PPI二联疗法的患者,差异有统计学意义(P<0.05)。结论：与胃黏膜活检Hp方法相比,13C-UBT方法在Hp的检出上具有较高的准确度、特异性和敏感度,同时操作简单、对人体无害和非侵入性等优点,是儿童Hp感染慢性胃炎的理想诊断方法,值得在儿科推广和应用。
목적：：대만성위염인동환자13C-뇨소호기시험(13C-UBT)화위점막활체조직검사(활검)Hp량충검측방법진행비교분석。방법：선취아원수치적만성위염인동환자46례,분별진행13C-뇨소호기시험검측화위점막활검Hp검측,병이위점막활검Hp검측결과위표준,비교13C-UBT대유문라선간균검출적준학도、특이성화민감도；병대검측출Hp양성환자채용질자빙억제제(PPI)진행치료,관찰기림상료효。결과：위점막활검Hp검측결과현시,13C-UBT적준학도、특이성화민감도분별위97.83%、92.86%화100%,차대Hp양성환자채용PPI삼련요법치료적전음솔요현저우우채용단순PPI화PPI이련요법적환자,차이유통계학의의(P<0.05)。결론：여위점막활검Hp방법상비,13C-UBT방법재Hp적검출상구유교고적준학도、특이성화민감도,동시조작간단、대인체무해화비침입성등우점,시인동Hp감염만성위염적이상진단방법,치득재인과추엄화응용。
Objective:To children chronic gastritis patients 13 c-UBT and gastric mucosal biopsies Hp two kinds of detection methods comparative analysis.Methods:The patients of chronic gastritis,46 cases of children were 13 c-urea breath test and gastric mucosal biopsies Hp testing,more 13 c-UBT for helicobacter pylori detection accuracy,specificity and sensitivity,And the detection of Hp positive patients treated by PPI and to observe its efficacy.Results:The gastric mucosal biopsies Hp testing results showed that 13 c-UBT accuracy,specificity and sensitivity were 97.83%,92.86%and 100%,and the PPI triple therapy,shade rate was superior to pure PPI and PPI duplex therapy,significant difference (P<0.05).Conclusion:And gastric mucosal biopsy method than Hp,13 c-UBT method in Hp's detection has higher accuracy,specificity and sensitivity,and at the same time,the operation is simple,harmless to the human body and non-invasive etc.