中国医药导刊
中國醫藥導刊
중국의약도간
CHINESE JOURNAL OF MEDICAL GUIDE
2013年
10期
1671-1672,1674
,共3页
甘露聚糖肽%序贯%急性盆腔炎%腹腔镜手术
甘露聚糖肽%序貫%急性盆腔炎%腹腔鏡手術
감로취당태%서관%급성분강염%복강경수술
Mannatide%Sequential therapy%Acute pelvic inflammatory disease%Laparoscopic surgery
目的：：探讨甘露聚糖肽序贯联合腹腔镜手术治疗急性盆腔炎的临床疗效。方法：急性盆腔炎患者96例按抽签方式随机分为治疗组和对照组,各48例,对照组行腹腔镜手术治疗,并给予常规治疗药物,治疗组在对照组治疗基础上序贯给予甘露聚糖肽,观察治疗前后临床体征、T淋巴细胞亚群、NK细胞数量等指标。结果：治疗组总有效率97.92%,略高于对照组(91.67%),两组比较差异无统计学意义(χ2=0.84,P=0.36)。但治疗组平均住院时间、体温恢复时间、疼痛持续时间、使用抗生素时间均较对照组明显缩短(P<0.05),T淋巴细胞亚群、NK细胞数量均较对照组显著提高(P<0.05)。随访1年中治疗组无复发病例,与对照组(复发率为8.33%)比较差异具有统计学意义(χ2=4.17,P=0.041)。结论：甘露聚糖肽序贯辅助腹腔镜手术治疗急性盆腔炎能提高免疫功能,缩短恢复时间,降低术后复发率。
目的：：探討甘露聚糖肽序貫聯閤腹腔鏡手術治療急性盆腔炎的臨床療效。方法：急性盆腔炎患者96例按抽籤方式隨機分為治療組和對照組,各48例,對照組行腹腔鏡手術治療,併給予常規治療藥物,治療組在對照組治療基礎上序貫給予甘露聚糖肽,觀察治療前後臨床體徵、T淋巴細胞亞群、NK細胞數量等指標。結果：治療組總有效率97.92%,略高于對照組(91.67%),兩組比較差異無統計學意義(χ2=0.84,P=0.36)。但治療組平均住院時間、體溫恢複時間、疼痛持續時間、使用抗生素時間均較對照組明顯縮短(P<0.05),T淋巴細胞亞群、NK細胞數量均較對照組顯著提高(P<0.05)。隨訪1年中治療組無複髮病例,與對照組(複髮率為8.33%)比較差異具有統計學意義(χ2=4.17,P=0.041)。結論：甘露聚糖肽序貫輔助腹腔鏡手術治療急性盆腔炎能提高免疫功能,縮短恢複時間,降低術後複髮率。
목적：：탐토감로취당태서관연합복강경수술치료급성분강염적림상료효。방법：급성분강염환자96례안추첨방식수궤분위치료조화대조조,각48례,대조조행복강경수술치료,병급여상규치료약물,치료조재대조조치료기출상서관급여감로취당태,관찰치료전후림상체정、T림파세포아군、NK세포수량등지표。결과：치료조총유효솔97.92%,략고우대조조(91.67%),량조비교차이무통계학의의(χ2=0.84,P=0.36)。단치료조평균주원시간、체온회복시간、동통지속시간、사용항생소시간균교대조조명현축단(P<0.05),T림파세포아군、NK세포수량균교대조조현저제고(P<0.05)。수방1년중치료조무복발병례,여대조조(복발솔위8.33%)비교차이구유통계학의의(χ2=4.17,P=0.041)。결론：감로취당태서관보조복강경수술치료급성분강염능제고면역공능,축단회복시간,강저술후복발솔。
Objective:To investigate the clinical efficacy of sequential Mannatide therapy combined with laparoscopic surgery for the patients with acute pelvic inflammatory disease (APID).Methods:A total of 96 patients with APID were randomly divided into 2 groups:48 in the control group (laparoscopic surgery with conventional drugs) and 48 in the treatment group(sequential Mannatide therapy plus the same treatment used in the control group).Clinical signs,T-lymphocyte subsets and the number of NK cells were observed before and after treatment.Results:Total effective rate (97.92%VS91.67%) of the treatment group were superior to the control group,there was no statistical significance between the two groups (χ2=0.84,P=0.36).The average length of stay,body temperature recovery time,pain duration and the use of antibiotics in time of the treatment group were significantly shorter than that of the control group (P<0.05).T-lymphocyte subsets,NK cell numbers experienced a significant increasing compared with the control group (P<0.05).The 1 year (0 VS 8.33%) recurrence rate of the treatment group was lower than the control group with significant difference (χ2=4.17,P=0.041).Conclusion:The use of sequential Mannatide therapy combined with laparoscopic surgery for APID can enhance immune function,shorten the recovery time and reduce the recurrence rate.
