中国临床新医学
中國臨床新醫學
중국림상신의학
CHINESE JOURNAL OF NEW CLINICAL MEDICINE
2013年
10期
987-989
,共3页
原发性肝癌%肝动脉化疗%体部立体定向放疗
原髮性肝癌%肝動脈化療%體部立體定嚮放療
원발성간암%간동맥화료%체부입체정향방료
Primary liver cancer%Transcatheter hepatic arterial chemomembolization( TACE)%Ster-eotactic body radiation(SBRT)
目的:探讨肝动脉介入化疗(TACE)联合体部立体定向放射治疗(SBRT)原发性肝癌的近期疗效和毒副作用。方法对收治的PS评分≥2分的原发性肝癌患者58例予以TACE联合陀螺旋转式钴60 SBRT治疗,随访观察患者疗效及毒副反应。结果58例患者中完全缓解10例(17.24%),部分缓解21例(36.21%),稳定20例(34.48%),进展7例(12.07%)。总有效率为53.45%。1年局部控制率为36.21%,1年总生存率为62.07%。结论 TACE联合SBRT治疗原发性肝癌的近期疗效好,毒副作用低,远期疗效需进一步观察。
目的:探討肝動脈介入化療(TACE)聯閤體部立體定嚮放射治療(SBRT)原髮性肝癌的近期療效和毒副作用。方法對收治的PS評分≥2分的原髮性肝癌患者58例予以TACE聯閤陀螺鏇轉式鈷60 SBRT治療,隨訪觀察患者療效及毒副反應。結果58例患者中完全緩解10例(17.24%),部分緩解21例(36.21%),穩定20例(34.48%),進展7例(12.07%)。總有效率為53.45%。1年跼部控製率為36.21%,1年總生存率為62.07%。結論 TACE聯閤SBRT治療原髮性肝癌的近期療效好,毒副作用低,遠期療效需進一步觀察。
목적:탐토간동맥개입화료(TACE)연합체부입체정향방사치료(SBRT)원발성간암적근기료효화독부작용。방법대수치적PS평분≥2분적원발성간암환자58례여이TACE연합타라선전식고60 SBRT치료,수방관찰환자료효급독부반응。결과58례환자중완전완해10례(17.24%),부분완해21례(36.21%),은정20례(34.48%),진전7례(12.07%)。총유효솔위53.45%。1년국부공제솔위36.21%,1년총생존솔위62.07%。결론 TACE연합SBRT치료원발성간암적근기료효호,독부작용저,원기료효수진일보관찰。
Objective To explore the recent curative efficacies and adverse responses of the transcatheter hepatic arterial chemomembolization (TACE)combined with stereotactic radiotherapy (SBRT) in the treatment of pa-tients with primary liver cancer .Methods Fifty-eight patients with primary liver cancer who had physical status score ≥2 were given TACE combined with gyro knife Co 60 SBRT.All patients were followed up to observe curative effects and adverse responses .Results Total 58 patients had received the treatment .Ten patients(17.24%) reached com-plete response, 21 patients(36.21%) partial response, 20(34.48%) stable disease and 7 (12.07%) disease pro-gression.The overall objective rate was 53.45%, one year local control rate 36.21%and 1 year overall survival rate 62.07%.Conclusion The TACE combined with SBRT in the treatmeng of primary liver cancer displayed good re -cent curative efficacies , but low response rate of side effects .The long-term efficacies deserve further observation .