CAJ | 학술논문

时间飞跃法磁共振血管成像%重叠多个簿层块采集%倾斜优化非饱和激励%磁化传递%最大密度投影重建%1.5T磁共振扫描仪時間飛躍法磁共振血管成像%重疊多箇簿層塊採集%傾斜優化非飽和激勵%磁化傳遞%最大密度投影重建%1.5T磁共振掃描儀
시간비약법자공진혈관성상%중첩다개부층괴채집%경사우화비포화격려%자화전체%최대밀도투영중건%1.5T자공진소묘의
time-of-lfight magnetic resonance angiography%multiple overlapped thin slab acquisition%tilt optimized non-saturation excitation%magnetization transfer%maximum intensity projection reconstruction%1.5T magnetic resonance angiography scanner

目的：探讨组合应用重叠多个簿层块采集（MOTSA）、倾斜优化非饱和激励（TONE）及磁化传递（MT）对时间飞跃法磁共振血管成像（TOF-MRA）图像质量及扫描时间的影响。方法回顾分析50例健康志愿者TOF-MRA扫描资料，同时采用不同参数组合的6个序列所得原始图像及最大密度投影（MIP）重建图像，6个序列分别是：TOF-MOTSA28（20%）-TONE-MT、TOF-MOTSA28（28.57%）-TONE-MT、TOF-MOTSA40（20%）-TONE-MT、TOF-MOTSA56（20%）-TONE-MT、TOF-MOTSA40（20%）-MT、TOF-MOTSA40（20%）-TONE （MOTSA28、MOTSA40、MOTSA56分别表示单个薄层块内的层数为28、40、56，20%或28.57%表示块重叠比例）。对比各序列MIP重建图像完整度、均匀度、相邻块之间血管移行平滑度及扫描时间（折算成采集相同有效层数的扫描时间）。结果50例TOF-MOTSA28(20%)-TONE-MT块交界处“血管中断”，其他序列无“血管中断”现象；50例TOF-MOTSA28(28.57%)-TONE-MT的采集时间最长，48例图像完整、均匀地显示出容积动脉、相邻块之间血管移行平滑；45例TOF-MOTSA40(20%)-TONE-MT图像完整、均匀地显示出容积动脉、相邻块之间血管移行平滑；33例TOF-MOTSA56(20%)-TONE-MT的平行走行血管信号减低；35例TOF-MOTSA40(20%)-MT的流出端信号减低；50例TOF-MOTSA40(20%)-TONE采集时间最短，其中36例末梢血管信号降低或消失。结论应用3D-TOF-MRA序列进行颅脑血管成像时多种技术组合应用能更有效地减轻血流饱和效应，增强慢速血流和末梢血流信号；多种技术的合理配置能在保证图像质量的同时进一步缩短扫描时间。
목적：탐토조합응용중첩다개부층괴채집（MOTSA）、경사우화비포화격려（TONE）급자화전체（MT）대시간비약법자공진혈관성상（TOF-MRA）도상질량급소묘시간적영향。방법회고분석50례건강지원자TOF-MRA소묘자료，동시채용불동삼수조합적6개서렬소득원시도상급최대밀도투영（MIP）중건도상，6개서렬분별시：TOF-MOTSA28（20%）-TONE-MT、TOF-MOTSA28（28.57%）-TONE-MT、TOF-MOTSA40（20%）-TONE-MT、TOF-MOTSA56（20%）-TONE-MT、TOF-MOTSA40（20%）-MT、TOF-MOTSA40（20%）-TONE （MOTSA28、MOTSA40、MOTSA56분별표시단개박층괴내적층수위28、40、56，20%혹28.57%표시괴중첩비례）。대비각서렬MIP중건도상완정도、균균도、상린괴지간혈관이행평활도급소묘시간（절산성채집상동유효층수적소묘시간）。결과50례TOF-MOTSA28(20%)-TONE-MT괴교계처“혈관중단”，기타서렬무“혈관중단”현상；50례TOF-MOTSA28(28.57%)-TONE-MT적채집시간최장，48례도상완정、균균지현시출용적동맥、상린괴지간혈관이행평활；45례TOF-MOTSA40(20%)-TONE-MT도상완정、균균지현시출용적동맥、상린괴지간혈관이행평활；33례TOF-MOTSA56(20%)-TONE-MT적평행주행혈관신호감저；35례TOF-MOTSA40(20%)-MT적류출단신호감저；50례TOF-MOTSA40(20%)-TONE채집시간최단，기중36례말소혈관신호강저혹소실。결론응용3D-TOF-MRA서렬진행로뇌혈관성상시다충기술조합응용능경유효지감경혈류포화효응，증강만속혈류화말소혈류신호；다충기술적합리배치능재보증도상질량적동시진일보축단소묘시간。
Objective To explore the effects of combination of multiple techniques including MOTSA (Multiple Overlapped Thin Slab Acquisition), TONE (Tilt Optimized Non-saturation Excitation) and MT (Magnetization Transfer) on TOF-MRA (Time-of-lfight Magnetic Resonance Angiography) imaging quality and the scanning time. Methods TOF-MRA was performed in 50 healthy volunteers recruited in this study with deployment of six different scanning sequences so as to obtain the original images, and MIP (Maximum Intensity Projection) reconstruction was applied thereafter. The six scanning sequences included TOF-MOTSA28(20%)-TONE-MT, TOF-MOTSA28(28.57%)-TONE-MT, TOF-MOTSA40(20%)-TONE-MT, TOF-MOTSA56(20%)-TONE-MT, TOF-MOTSA40(20%)-MT and TOF-MOTSA40(20%)-TONE (MOTSA28, MOTSA40 and MOTSA56 indicated that the number of slice per thin slab was 28, 40 and 56 respectively;whereas 20%or 28.57%referred to the proportion of the overlapped thin slab). Then, comparisons were made among MIP-reconstructed images obtained using the six scanning sequences in the completeness, uniformity, smoothness in vascular transition between adjacent slabs and the time consumed in each scanning procedure (the scanning time herein is deifned as the time consumed in scanning under the same number of effective slice). Results Vessel interruption was shown at the junction of the slab in 50 MIP-reconstructed images obtained in the sequence of TOF-MOTSA28(20%)-TONE-MT; whereas no vessel interruption was found in images obtained in other sequences. Scanning with the sequence of TOF-MOTSA28(28.57%)-TONE-MT in 50 volunteers was the most time-consuming in comparison with those with other sequences;among 50 images obtained in the sequence of TOF-MOTSA28(28.57%)-TONE-MT, 48 had complete and uniform manifestations of volume arteries and smooth vascular transition between adjacent slabs. MIP-reconstructed images obtained with the sequence of TOF-MOTSA40(20%)-TONE-MT in 45 volunteers were complete and uniform in demonstration of volume arteries and smooth vascular transition between adjacent slabs. The scanning sequences of TOF-MOTSA56(20%)-TONE-MT and TOF-MOTSA40(20%)-MT resulted in decreased signals of the parallelly-distributed vessels in 33 cases and the outlets in 35 cases respectively. Among 50 images obtained in the most time-saving sequence - TOF-MOTSA40(20%)-TONE in comparison with deployment of other sequences, 36 cases showed decreased or disappearing signals in peripheral vessels. Conclusion Deployment of combination of multiple techniques in craniocerebral angiography in the 3D-TOF-MRA sequences can mitigate the saturation effect of blood flow more effectively and enhance the signals in the slow and peripheral blood lfow. Optimized conifgurations of multiple techniques can permit the time-saving acquisition of high-quality images.