中医药导报
中醫藥導報
중의약도보
GUIDING JOURNAL OF TCM
2013年
10期
10-12
,共3页
蔡欣蕊%钱卫斌%姜群群%李群英%钱秋海
蔡訢蕊%錢衛斌%薑群群%李群英%錢鞦海
채흔예%전위빈%강군군%리군영%전추해
甲亢合并肝损伤%甲状腺功能%肝功能%基础代谢率%甲亢宁
甲亢閤併肝損傷%甲狀腺功能%肝功能%基礎代謝率%甲亢寧
갑항합병간손상%갑상선공능%간공능%기출대사솔%갑항저
Hyperthyroidism with liver injury%Thyroid function%Liver function%Basal metabolic rate%Jiakangning
目的：观察甲亢宁治疗甲亢合并肝损伤的临床疗效。方法：将160例甲亢合并肝损伤患者随机分为治疗组和对照组各80例。治疗组予甲亢宁及基础治疗，对照组予天晴甘平及基础治疗，治疗12周后观察两组患者的FT3、FT4、TSH、基础代谢率、ALT、AST、ALP、γ-GT、TBiL。结果：治疗12周后，两组患者的TSH水平均升高，FT3、FT4、BMR均降低，差异有统计学意义（P＜0.01）；两组治疗后比较，治疗组FT3、FT4、BMR均低于对照组（P＜0.01），TSH高于对照组（P＜0.01）。治疗12周后，治疗组患者的ALT、AST、ALP、γ-GT、TBIL水平均降低（P<0.01或P<0.05），对照组治疗后ALT、AST、ALP水平均降低（P<0.01）；两组治疗后比较，治疗组ALT、AST、ALP、γ-GT、TBIL均低于对照组，差异有统计学意义（P<0.01或P<0.05）。结论：应用甲亢宁可明显纠正甲状腺功能亢进症合并肝损患者的甲状腺功能及基础代谢率，同时能降低相关肝功能指标，减轻肝脏损害。
目的：觀察甲亢寧治療甲亢閤併肝損傷的臨床療效。方法：將160例甲亢閤併肝損傷患者隨機分為治療組和對照組各80例。治療組予甲亢寧及基礎治療，對照組予天晴甘平及基礎治療，治療12週後觀察兩組患者的FT3、FT4、TSH、基礎代謝率、ALT、AST、ALP、γ-GT、TBiL。結果：治療12週後，兩組患者的TSH水平均升高，FT3、FT4、BMR均降低，差異有統計學意義（P＜0.01）；兩組治療後比較，治療組FT3、FT4、BMR均低于對照組（P＜0.01），TSH高于對照組（P＜0.01）。治療12週後，治療組患者的ALT、AST、ALP、γ-GT、TBIL水平均降低（P<0.01或P<0.05），對照組治療後ALT、AST、ALP水平均降低（P<0.01）；兩組治療後比較，治療組ALT、AST、ALP、γ-GT、TBIL均低于對照組，差異有統計學意義（P<0.01或P<0.05）。結論：應用甲亢寧可明顯糾正甲狀腺功能亢進癥閤併肝損患者的甲狀腺功能及基礎代謝率，同時能降低相關肝功能指標，減輕肝髒損害。
목적：관찰갑항저치료갑항합병간손상적림상료효。방법：장160례갑항합병간손상환자수궤분위치료조화대조조각80례。치료조여갑항저급기출치료，대조조여천청감평급기출치료，치료12주후관찰량조환자적FT3、FT4、TSH、기출대사솔、ALT、AST、ALP、γ-GT、TBiL。결과：치료12주후，량조환자적TSH수평균승고，FT3、FT4、BMR균강저，차이유통계학의의（P＜0.01）；량조치료후비교，치료조FT3、FT4、BMR균저우대조조（P＜0.01），TSH고우대조조（P＜0.01）。치료12주후，치료조환자적ALT、AST、ALP、γ-GT、TBIL수평균강저（P<0.01혹P<0.05），대조조치료후ALT、AST、ALP수평균강저（P<0.01）；량조치료후비교，치료조ALT、AST、ALP、γ-GT、TBIL균저우대조조，차이유통계학의의（P<0.01혹P<0.05）。결론：응용갑항저가명현규정갑상선공능항진증합병간손환자적갑상선공능급기출대사솔，동시능강저상관간공능지표，감경간장손해。
Objective: To observe the effect of Jiakangning on hyperthyroidism patients with hepatic injury. Methods: 160 hyperthyroidism patients with hepatic injury were randomly divided into treatment and control groups. Patients were treated with Jiakangning in treatment group and Diammonium Glycyrrhizinate in control group. The FT3, FT4, TSH, basal metabolic rate, ALT, AST, ALP, γ-GT and TBiL were observed after 12 weeks. Results: TSH levels were elevated and the FT3, FT4, BMR were lowered in treatment and control groups, with statistically significant difference (P<0.01). After treatment, the FT3, FT4 and BMR in treatment group were lower than that of the control group, TSH higher than that of the control group (P<0.01). ALT, AST, ALP, γ-GT and TBIL levels decreased in treatment group (P<0.01 or P<0.05). ALT, AST and ALP levels were lower in control group after treatment (P<0.01). After treatment, ALT, AST, ALP, γ-GT, TBIL in treatment group were lower than that in control group and the difference was statistically significant (P<0.01 or P<0.05). Conclusion: Jiakangning can balance the Thyroid function and make the liver function better.
