大理学院学报
大理學院學報
대이학원학보
JOURNAL OF DALI COLLEGE
2013年
12期
43-49
,共7页
重症监护室%感染%病原菌%耐药性
重癥鑑護室%感染%病原菌%耐藥性
중증감호실%감염%병원균%내약성
intensive care unit(ICU)%infection%pathogenic bacteria%resistance
目的：回顾性的分析某医院重症监护室（ICU）2012年1月1日至2012年12月31日之间感染病原菌的分布及其耐药情况。方法：用VITET-2Compact60全自动微生物分析仪鉴定细菌，K-B纸片扩散法做体外药敏试验，统计、分析细菌的检出率和药敏结果。结果：799份ICU标本，医院感染分离菌株249株，检出率31.16%。首位是洋葱伯克霍尔德菌（60株，24.10%），其次鲍曼不动杆菌（55株，22.09%），第三是肺炎克雷伯菌（39株，15.66%）。分离菌中标本来源痰和咽拭子最常见，其次静脉血、静脉导管。洋葱假单胞、鲍曼不动杆菌、铜绿假单胞菌、肺炎克雷伯菌、大肠埃希菌、人葡萄球菌及金黄色葡萄球菌对多种抗菌药物均具有较高的耐药性。结论：医院感染病原菌中以非发酵菌的检出率最高，其次是肺炎克雷伯菌并且耐药性强。因此治疗医院感染病原菌所致的感染性疾病应根据体外药敏试验结果选用敏感的抗菌药物，减低耐药率。
目的：迴顧性的分析某醫院重癥鑑護室（ICU）2012年1月1日至2012年12月31日之間感染病原菌的分佈及其耐藥情況。方法：用VITET-2Compact60全自動微生物分析儀鑒定細菌，K-B紙片擴散法做體外藥敏試驗，統計、分析細菌的檢齣率和藥敏結果。結果：799份ICU標本，醫院感染分離菌株249株，檢齣率31.16%。首位是洋蔥伯剋霍爾德菌（60株，24.10%），其次鮑曼不動桿菌（55株，22.09%），第三是肺炎剋雷伯菌（39株，15.66%）。分離菌中標本來源痰和嚥拭子最常見，其次靜脈血、靜脈導管。洋蔥假單胞、鮑曼不動桿菌、銅綠假單胞菌、肺炎剋雷伯菌、大腸埃希菌、人葡萄毬菌及金黃色葡萄毬菌對多種抗菌藥物均具有較高的耐藥性。結論：醫院感染病原菌中以非髮酵菌的檢齣率最高，其次是肺炎剋雷伯菌併且耐藥性彊。因此治療醫院感染病原菌所緻的感染性疾病應根據體外藥敏試驗結果選用敏感的抗菌藥物，減低耐藥率。
목적：회고성적분석모의원중증감호실（ICU）2012년1월1일지2012년12월31일지간감염병원균적분포급기내약정황。방법：용VITET-2Compact60전자동미생물분석의감정세균，K-B지편확산법주체외약민시험，통계、분석세균적검출솔화약민결과。결과：799빈ICU표본，의원감염분리균주249주，검출솔31.16%。수위시양총백극곽이덕균（60주，24.10%），기차포만불동간균（55주，22.09%），제삼시폐염극뢰백균（39주，15.66%）。분리균중표본래원담화인식자최상견，기차정맥혈、정맥도관。양총가단포、포만불동간균、동록가단포균、폐염극뢰백균、대장애희균、인포도구균급금황색포도구균대다충항균약물균구유교고적내약성。결론：의원감염병원균중이비발효균적검출솔최고，기차시폐염극뢰백균병차내약성강。인차치료의원감염병원균소치적감염성질병응근거체외약민시험결과선용민감적항균약물，감저내약솔。
Objective: To make a retrospective analysis of the infection pathogenic bacteria distribution and drug resistance in hospital intensive care unit (ICU) from January 1, 2012 to December 31, 2012. Methods: The identification of bacteria and susceptibility test were performed by using automatic bioanalysis-VITET-2 Compact 60 and Kirby-Bauer methods;the detection rate and the drug sensitivity results of bacterial were analyzed statistically. Results: 799 ICU specimens, 249 strains of hospital infection isolates, the detection rate of 31.16%. The first three bacteria in these samples were:onion burkholderia bacteria topped (60 strains, 24.10%), acinetobacter baumannii followed(55 cases, 22.09%), klebsiella pneumoniae was the third(39 strains, 15.66%). Isolated bacteria in sputum specimen source and pharyngeal swab the most common, followed by venous blood and venous catheter. Onion false unit cell, acinetobacter baumannii, pseudomonas aeruginosa, klebsiella pneumoniae and e. coli, staphylococcus aureus and staphylococcus aureus were with high resistance to many kinds of antimicrobial agents. Conclusion: The detection rate of fermentation bacteria in nosocomial infection pathogens is highest, followed by klebsiella pneumoniae and its resistance is strong; so the treatment of hospital infection caused by pathogens of infectious diseases should be selected according to results of fungi susceptibility test in vitro sensitive antimicrobial agents, in order to reduce resistance.
