大理学院学报
大理學院學報
대이학원학보
JOURNAL OF DALI COLLEGE
2013年
12期
39-42
,共4页
尿路感染%大肠埃希菌%超广谱β-内酰胺酶%细菌耐药性
尿路感染%大腸埃希菌%超廣譜β-內酰胺酶%細菌耐藥性
뇨로감염%대장애희균%초엄보β-내선알매%세균내약성
urinary tract infection%Escherichia coli%ESBLs%drug resistance of bacteria
目的：了解保山某院尿路感染病原菌的分布情况及大肠埃希菌的耐药情况，为临床合理使用抗生素提供依据。方法：用VITET-2 Compact60全自动微生物分析仪鉴定细菌，K-B纸片扩散法做体外药敏试验，统计、分析细菌的检出率和药敏结果。结果：尿路感染病原菌占第一位的是大肠埃希菌（74.2%），其次为肺炎克雷伯菌（10%），次之为表皮葡萄球菌（4.3%）；病原菌在临床各科室分布情况为泌尿科45.7%、康复科20%、ICU 14.3%；52株大肠埃希菌对13种抗生素的耐药率居前三位的分别为：氨苄西林98%、复方新诺明76.9%、庆大霉素65.4%，52株大肠埃希菌对厄他培南、亚胺培南均敏感；52株大肠埃希菌中产ESBLs的29株占55.8%，非产ESBLs的23株占44.2%。结论：医院尿路感染病原菌以大肠埃希菌为主，科室分布以泌尿科为首，尿路感染大肠埃希菌的耐药情况较严重，医院应加强其耐药性监测，医生应依据体外药敏试验结果合理选择抗生素。
目的：瞭解保山某院尿路感染病原菌的分佈情況及大腸埃希菌的耐藥情況，為臨床閤理使用抗生素提供依據。方法：用VITET-2 Compact60全自動微生物分析儀鑒定細菌，K-B紙片擴散法做體外藥敏試驗，統計、分析細菌的檢齣率和藥敏結果。結果：尿路感染病原菌佔第一位的是大腸埃希菌（74.2%），其次為肺炎剋雷伯菌（10%），次之為錶皮葡萄毬菌（4.3%）；病原菌在臨床各科室分佈情況為泌尿科45.7%、康複科20%、ICU 14.3%；52株大腸埃希菌對13種抗生素的耐藥率居前三位的分彆為：氨芐西林98%、複方新諾明76.9%、慶大黴素65.4%，52株大腸埃希菌對阨他培南、亞胺培南均敏感；52株大腸埃希菌中產ESBLs的29株佔55.8%，非產ESBLs的23株佔44.2%。結論：醫院尿路感染病原菌以大腸埃希菌為主，科室分佈以泌尿科為首，尿路感染大腸埃希菌的耐藥情況較嚴重，醫院應加彊其耐藥性鑑測，醫生應依據體外藥敏試驗結果閤理選擇抗生素。
목적：료해보산모원뇨로감염병원균적분포정황급대장애희균적내약정황，위림상합리사용항생소제공의거。방법：용VITET-2 Compact60전자동미생물분석의감정세균，K-B지편확산법주체외약민시험，통계、분석세균적검출솔화약민결과。결과：뇨로감염병원균점제일위적시대장애희균（74.2%），기차위폐염극뢰백균（10%），차지위표피포도구균（4.3%）；병원균재림상각과실분포정황위비뇨과45.7%、강복과20%、ICU 14.3%；52주대장애희균대13충항생소적내약솔거전삼위적분별위：안변서림98%、복방신낙명76.9%、경대매소65.4%，52주대장애희균대액타배남、아알배남균민감；52주대장애희균중산ESBLs적29주점55.8%，비산ESBLs적23주점44.2%。결론：의원뇨로감염병원균이대장애희균위주，과실분포이비뇨과위수，뇨로감염대장애희균적내약정황교엄중，의원응가강기내약성감측，의생응의거체외약민시험결과합리선택항생소。
Objective: To understand the distribution of causative organisms in urinary tract infection and drug resistance of Escherichia coli in a hospital located in Baoshan in order to provide clinicians the basis for rational use of antibiotics. Methods:The identification of bacteria and susceptibility test were performed by using automatic bioanalysis- VITET-2 Compact 60 and Kirby-Bauer methods; the detection rate and the drug sensitivity results of bacterial were analyzed statistically. Results: The first three detection rates of causative bacteria in urine samples were: Escherichia coli topped (74.2%), Klebsiella pneumoniae followed (10%), Staphylococcus epidermidis was third (4.3%). The detection rates of causative bacteria in the top three clinical departments were:department of urology 45.7%, department of rehabilitation 20%, ICU 14.3%. The top three drug resistance rates of 52 strains of Escherichia coli to 13 kinds of antibiotics were: ampicillin 98%, cotrimoxazole 76.9%, gentamicin 65.4%. All the strains of Escherichia coli were sensitive to ertapenem and imipenem; 29 cases of ESBL-producing Escherichia coli accounted for 55.8%, 23 cases of non ESBL-producing ones accounted for 44.2%. Conclusion: Escherichia coli are in the majority of urinary tract infections caused by organisms in hospital. The infectious cases in urinary department are first in the distribution of clinical departments. Since the drug resistance of Escherichia coli in urinary tract infection is serious, the hospital should strengthen monitoring of drug resistance of Escherichia coli and doctors should select antibiotics based on the results of drug sensitivity test in vitro.
