医学信息
醫學信息
의학신식
MEDICAL INFORMATION
2013年
13期
209-209,210
,共2页
早产预测%胰岛素样生长因子结合蛋白-1%会阴超声
早產預測%胰島素樣生長因子結閤蛋白-1%會陰超聲
조산예측%이도소양생장인자결합단백-1%회음초성
Premature to predict%Insulin like growth factor binding protein-1%Perineal ultrasound
目的探讨检测早产高危孕妇宫颈分泌物中高磷酸化胰岛素样生长因子结合蛋白-1(ph IGFBP -1)、会阴超声检查宫颈长度预测早产的价值。方法孕28～36w用分娩预测试纸检测宫颈分泌物中 ph IGFBP -1(Actim Partus test),同时会阴超声检测宫颈长度( cervical length, CL),观察记录分娩结局。结果IGFBP-1、宫颈指数阳性组中早产发生率明显高于阴性组（P＜0.01），该两指标联合应用对早产的阳性预测值明显提高（P＜0.01）。两指标阳性组48h内分娩率为50%，1w内分娩率为70%，距离分娩时间明显短于单一指标阳性组及两指标阴性组（P＜0.01）。而两指标阴性组2w内分娩的阴性预测值为100%。血清CRP在早产组与足月产组间无统计学差异（P＞0.05）。结论宫颈长度联合ph IGFBP-1检测对预测早产有较高的价值。
目的探討檢測早產高危孕婦宮頸分泌物中高燐痠化胰島素樣生長因子結閤蛋白-1(ph IGFBP -1)、會陰超聲檢查宮頸長度預測早產的價值。方法孕28～36w用分娩預測試紙檢測宮頸分泌物中 ph IGFBP -1(Actim Partus test),同時會陰超聲檢測宮頸長度( cervical length, CL),觀察記錄分娩結跼。結果IGFBP-1、宮頸指數暘性組中早產髮生率明顯高于陰性組（P＜0.01），該兩指標聯閤應用對早產的暘性預測值明顯提高（P＜0.01）。兩指標暘性組48h內分娩率為50%，1w內分娩率為70%，距離分娩時間明顯短于單一指標暘性組及兩指標陰性組（P＜0.01）。而兩指標陰性組2w內分娩的陰性預測值為100%。血清CRP在早產組與足月產組間無統計學差異（P＞0.05）。結論宮頸長度聯閤ph IGFBP-1檢測對預測早產有較高的價值。
목적탐토검측조산고위잉부궁경분비물중고린산화이도소양생장인자결합단백-1(ph IGFBP -1)、회음초성검사궁경장도예측조산적개치。방법잉28～36w용분면예측시지검측궁경분비물중 ph IGFBP -1(Actim Partus test),동시회음초성검측궁경장도( cervical length, CL),관찰기록분면결국。결과IGFBP-1、궁경지수양성조중조산발생솔명현고우음성조（P＜0.01），해량지표연합응용대조산적양성예측치명현제고（P＜0.01）。량지표양성조48h내분면솔위50%，1w내분면솔위70%，거리분면시간명현단우단일지표양성조급량지표음성조（P＜0.01）。이량지표음성조2w내분면적음성예측치위100%。혈청CRP재조산조여족월산조간무통계학차이（P＞0.05）。결론궁경장도연합ph IGFBP-1검측대예측조산유교고적개치。
Objective To investigate the detection of high risk premature cervical secretions in highly phosphorylated insulin-like growth factor binding protein - 1 ( pH IGFBP 1 ), perineal ultrasound examination of cervical length for predicting preterm delivery value. Methods Between 28 -36 weeks for delivery as predictors of test paper for detecting the cervical secretion in pH IGFBP 1 ( Actim Partus test ), at the same time transperineal ultrasound detection of cervical length ( cervical length, CL ), observe and record the outcome of childbirth. Results The incidence of preterm birth was significantly higher than that of negative group, cervical index in IGFBP-1 positive group ( P<0.01 ), positive predictive joint application of the two indexes of preterm birth was significantly increased ( P< 0.01 ). The two index was positive in 48 hours delivery rate was 50%, within 1 weeks of delivery rate was 70%, distance delivery time was shorter than the single index positive group and negative group two index ( P<0.01). Negative and two indexes of negative group within 2 weeks of delivery of the predictive value of 100%. Serum CRP showed no significant dif erence in the preterm group and term birth group ( P>0.05 ). Conclusion Cervical length and pH IGFBP-1 test in predicting preterm birth have a higher value.
