CAJ | 학술논문

目的：探讨自发荧光支气管镜（ AFB）在中央型支气管肺癌诊断中的价值。方法对93例临床怀疑支气管肺癌患者采用AFB联合白光支气管镜（ WLB）检查的诊断结果进行回顾性分析，统计AFB联合WLB和WLB的镜下异常表现及病理结果，比较两种方法诊断早期中央型肺癌的灵敏度、特异度。结果93例患者中，AFB联合WLB检查表现异常者79例，WLB检查表现异常者59例；74例患者病理诊断为阳性，其中重度非典型增生3例，原位癌1例，浸润性癌70例。 AFB联合WLB检查发现异常病理证实阳性者67例，WLB检查发现异常病理证实阳性者50例；两者诊断中央型肺癌的灵敏度分别为90?5％、67?6％，差异有统计学意义（P＜0?05）。结论对于中央型支气管肺癌的定位诊断，AFB 检查的灵敏度比 WLB更佳。
목적：탐토자발형광지기관경（ AFB）재중앙형지기관폐암진단중적개치。방법대93례림상부의지기관폐암환자채용AFB연합백광지기관경（ WLB）검사적진단결과진행회고성분석，통계AFB연합WLB화WLB적경하이상표현급병리결과，비교량충방법진단조기중앙형폐암적령민도、특이도。결과93례환자중，AFB연합WLB검사표현이상자79례，WLB검사표현이상자59례；74례환자병리진단위양성，기중중도비전형증생3례，원위암1례，침윤성암70례。 AFB연합WLB검사발현이상병리증실양성자67례，WLB검사발현이상병리증실양성자50례；량자진단중앙형폐암적령민도분별위90?5％、67?6％，차이유통계학의의（P＜0?05）。결론대우중앙형지기관폐암적정위진단，AFB 검사적령민도비 WLB경가。
Objective To investigate the value of using autofluorescence bronchoscopy( AFB) for the detection and localiza-tion of central type early lung cancer. Methods 93 patients,suspected of lung cancer were examinated by AFB and white light bron-choscopy( WLB) . All of the suspicious abnormal sites were recorded and biopsied for pathological examination. Two methods were com-pared by sensitivity and specificity. Results Included 93 biopsy specimens,and 74 were classified as positive by pathology,including 70 invasive cancer,1 carcinoma in situ and 3 severe dysplasia. AFB combined with WLB found positive resuts comfirmed by pathology in 67 cases, and WLB alone found positive in 50 cases. The relative sensitivity to detect central type early lung cancer of WLB com-bined with AFB versus WLB alone was 90?5% and 67?6%, respectively,with statistical difference significantly( P<0?05) . Conclusion The sensitivity of AFB is better than WLB in detection and localization of central type early lung cancer.