CAJ | 학술논문

妊娠期泛发性脓疱型银屑病是一种罕见而严重的银屑病。该病发病突然，发展迅速，以全身泛发无菌性脓疱伴严重全身症状为特征，常伴发热、白细胞增多和低蛋白血症等，病情严重，可危及母儿生命。妊娠期泛发性脓疱型银屑病的发病机制仍不清楚，糖皮质激素和维甲酸为治疗常用药物，但由于妊娠期用药受到限制，其治疗依然是非常棘手的问题。早期明确诊断、及时综合治疗并适时终止妊娠有望获得良好的母儿结局。现就妊娠期泛发性脓疱型银屑病的诊断及治疗研究进展进行综述。
임신기범발성농포형은설병시일충한견이엄중적은설병。해병발병돌연，발전신속，이전신범발무균성농포반엄중전신증상위특정，상반발열、백세포증다화저단백혈증등，병정엄중，가위급모인생명。임신기범발성농포형은설병적발병궤제잉불청초，당피질격소화유갑산위치료상용약물，단유우임신기용약수도한제，기치료의연시비상극수적문제。조기명학진단、급시종합치료병괄시종지임신유망획득량호적모인결국。현취임신기범발성농포형은설병적진단급치료연구진전진행종술。
Generalized pustular psoriasis of pregnancy is a rare and severe disease. The development is rapid ,with systemic generalized aseptic blain and severe systemic symptom for features,often associated with fever,hyperleukocytosis and hypoproteinemia,etc. It is a life-threatening disease either for pregnant woman or infant. The pathogenesis of the disease has not been illustrated completely. Glucocorticoid and retinoic acid are commonly used to treat this disease ,because the drugs used during pregnancy is restricted, the treatment is still difficult. Early diagnosis ,treatment and terminate pregnancy timely can improve the maternal and perinatal prognosis of this disease. This article is to review diagnosis and treatment progress of this disease.