CAJ | 학술논문

目的：探讨血液灌流联合连续性血液净化治疗急性重症胰腺炎的临床效果及应用价值。方法将我院治疗的80例急性重症胰腺炎患者分为观察组和对照组，对照组给予西医常规治疗，观察组在对照组治疗的基础上采取血液灌流联合连续性血液净化治疗，记录两组治疗情况。结果观察组心率、平均动脉压、血常规指标以及炎症因子改善均优于对照组，观察组患者病死率低于对照组，住院时间短于对照组，差异有统计学意义(P <0.01)。结论血液灌流联合连续性血液净化治疗急性重症胰腺炎效果可靠，能够明显降低体内炎症因子浓度，降低病死率且不增加并发症和治疗费用，值得在临床上大力推广使用。
목적：탐토혈액관류연합련속성혈액정화치료급성중증이선염적림상효과급응용개치。방법장아원치료적80례급성중증이선염환자분위관찰조화대조조，대조조급여서의상규치료，관찰조재대조조치료적기출상채취혈액관류연합련속성혈액정화치료，기록량조치료정황。결과관찰조심솔、평균동맥압、혈상규지표이급염증인자개선균우우대조조，관찰조환자병사솔저우대조조，주원시간단우대조조，차이유통계학의의(P <0.01)。결론혈액관류연합련속성혈액정화치료급성중증이선염효과가고，능구명현강저체내염증인자농도，강저병사솔차불증가병발증화치료비용，치득재림상상대력추엄사용。
Objective To explore the clinical significance and value of blood perfusion combined continu-ous blood purification therapy for severe acute pancreatitis. Methods Eighty hospitalized patients with se-vere acute pancreatitis were chosen in this study and were randomly assigned to an observation group and a con-trol group,the control group was given traditional western medicine treatment,and the observation group re-ceived the same traditional western medicine treatment as the control group plus blood perfusion combined with continuous blood purification therapy.The treatment course of the two groups was recorded. Results The observation group had better improvement in heart rate,mean arterial pressure,blood routine index and in-flammatory factor than the control group,the observation group had less fatality rate and shorter hospital du-ration than the control group,group paired comparison yielded statistically significant differences (P <0.01). Conclusion The results of blood perfusion combined continuous blood purification therapy for severe acute pancreatitis are reliable,and can significantly reduce body inflammation factor concentration,reduce fatality rate and does not increase complications and treatment costs,so it is worthwhile of clinical recommendation.