CAJ | 학술논문

目的：比较经螺旋型鼻肠管进行鼻空肠管肠内营养（NJEN）与常规肠外营养（PN）治疗重症急性胰腺炎（SAP）的临床效果，评价NJEN在重症急性胰腺炎治疗中的疗效和耐受性。方法：收集近4年本院33例SAP患者的资料，16例给予NJEN的患者为EN组，未进行NJEN的17例为常规组，比较两组患者营养支持后的临床检验生化指标情况及并发症转归情况。结果：治疗10 d后，EN组血清白蛋白显著升高，血白细胞和C-反应蛋白明显降低，总体并发症、转院、死亡例数下降，与常规组比较差异均有统计学意义（P<0.05）。结论：在SAP的营养支持治疗中，经螺旋型鼻肠管进行NJEN较以往常规治疗能更好的缓解炎症反应，改善营养状况，降低并发症发生率和病死率，避免转院带来的更多花费和风险，值得在基层单位推广。
목적：비교경라선형비장관진행비공장관장내영양（NJEN）여상규장외영양（PN）치료중증급성이선염（SAP）적림상효과，평개NJEN재중증급성이선염치료중적료효화내수성。방법：수집근4년본원33례SAP환자적자료，16례급여NJEN적환자위EN조，미진행NJEN적17례위상규조，비교량조환자영양지지후적림상검험생화지표정황급병발증전귀정황。결과：치료10 d후，EN조혈청백단백현저승고，혈백세포화C-반응단백명현강저，총체병발증、전원、사망례수하강，여상규조비교차이균유통계학의의（P<0.05）。결론：재SAP적영양지지치료중，경라선형비장관진행NJEN교이왕상규치료능경호적완해염증반응，개선영양상황，강저병발증발생솔화병사솔，피면전원대래적경다화비화풍험，치득재기층단위추엄。
Objective:To comparing nasojejunal enteral nutrition(NJEN)by spiral nasointestinal tube and conventional parenteral nutrition(PN) in the treatment of severe acute pancreatitis(SAP),in order to evaluate the excellence and efficacy of NJEN by spiral nasointestinal tube in the treatment of severe acute pancreatitis(SAP). Method:Thirty-three cases of SAP patient information were collected in our department nearly four years. The EN group(16 cases)were treated with NJEN,and other 17 patients in the conventional group without NJEN treatment. The clinical biochemical examination indicators of outcomes and complications of the situation were compared after giving the nutrition support. Result:White blood cells count and the levels of C-reactive protein were lowered significantly and the serum albumin were increased obviously in EN group after giving the nutrition support for 10 days, had significant difference compared with the conventional group(P<0.05). Conclusion:In nutrition support of SAP,NJEN by spiral nasointestinal tube is better than conventional treatment in the past in alleviate inflammation、improve nutritional status、reduce morbidity and mortality and avoid referral to bring more cost and risk. It is worth promoting in the grass-roots units.