中国保健营养（上旬刊）
中國保健營養（上旬刊）
중국보건영양（상순간）
China Health Care & Nutrition
2014年
6期
3054-3054
,共1页
HBV宫内感染%乙肝免疫球蛋白%临床观察
HBV宮內感染%乙肝免疫毬蛋白%臨床觀察
HBV궁내감염%을간면역구단백%림상관찰
HBV Intrauterine Infection%Hepatitis B Immunoglobulin%Clinical Observation
目的：探讨HBV宫内感染患者孕期应用乙肝免疫球蛋白的价值。方法选择2012年1月至2012年12月于我院收治的产检中检出乙型肝炎表面抗原阳性103例孕产妇，其中53例在孕期给予乙肝免疫球蛋白的孕妇及其新生儿作为观察组，其余50例未作特殊处理的孕妇及其新生儿作为对照组；比较产后两组新生儿HBV宫内感染的发生率情况。结果观察组新生儿HBV宫内感染的发生率在5％，较对照组20％明显降低，两组比较有显著差异性（P＜0．05）；且观察组中HbsAg（＋）3例，占5．7％，对照组HbsAg（＋）12例，占21．8％，两组比较有显著差异性（P＜0．05）。结论孕妇乙肝病毒感染可导致胎儿宫内感染，孕期注射乙肝免疫球蛋白及产后对新生儿进行联合免疫，可有效减少胎儿乙肝病毒感染的发生率，临床值得进一步研究应用。
目的：探討HBV宮內感染患者孕期應用乙肝免疫毬蛋白的價值。方法選擇2012年1月至2012年12月于我院收治的產檢中檢齣乙型肝炎錶麵抗原暘性103例孕產婦，其中53例在孕期給予乙肝免疫毬蛋白的孕婦及其新生兒作為觀察組，其餘50例未作特殊處理的孕婦及其新生兒作為對照組；比較產後兩組新生兒HBV宮內感染的髮生率情況。結果觀察組新生兒HBV宮內感染的髮生率在5％，較對照組20％明顯降低，兩組比較有顯著差異性（P＜0．05）；且觀察組中HbsAg（＋）3例，佔5．7％，對照組HbsAg（＋）12例，佔21．8％，兩組比較有顯著差異性（P＜0．05）。結論孕婦乙肝病毒感染可導緻胎兒宮內感染，孕期註射乙肝免疫毬蛋白及產後對新生兒進行聯閤免疫，可有效減少胎兒乙肝病毒感染的髮生率，臨床值得進一步研究應用。
목적：탐토HBV궁내감염환자잉기응용을간면역구단백적개치。방법선택2012년1월지2012년12월우아원수치적산검중검출을형간염표면항원양성103례잉산부，기중53례재잉기급여을간면역구단백적잉부급기신생인작위관찰조，기여50례미작특수처리적잉부급기신생인작위대조조；비교산후량조신생인HBV궁내감염적발생솔정황。결과관찰조신생인HBV궁내감염적발생솔재5％，교대조조20％명현강저，량조비교유현저차이성（P＜0．05）；차관찰조중HbsAg（＋）3례，점5．7％，대조조HbsAg（＋）12례，점21．8％，량조비교유현저차이성（P＜0．05）。결론잉부을간병독감염가도치태인궁내감염，잉기주사을간면역구단백급산후대신생인진행연합면역，가유효감소태인을간병독감염적발생솔，림상치득진일보연구응용。
Objective To discuss the value of application of hepatitis b immunoglobulin during pregnancy for patients with HBV intrauterine infection .Method 103 pregnant and lying-in women whose hepatitis b surface antigens were detected positive were chosen .Among them,53 women and their newborns were given hepatitis b immunoglobulins and marked as observation group while the other 50 women and their newborns were given no special treatments and marked as control group .Occur-rence rates of HBV intrauterine infection of newborns of the 2 groups were compared after deliveries.Result Occurrence rate of HBV intrauterine infection of newborns of observation group was 5% obviously lower than control group 20%(P<0.05);there were 3 cases of HbsAg( +)in observation group and accounted for 5.7% while 12 cases of HbsAg( +)in control group and accounted for 21.8%(P<0.05).Conclusion HBV infection of pregnant woman can lead to intrauterine infection of fetus.In-jection of hepatitis b immunoglobulin for pregnant woman during pregnancy and combined immunization for newborn can effectively reduce occurrence rate of HBV infec-tion.It needs to be further studied and applied.
