当代医学
噹代醫學
당대의학
CHINA CONTEMPORARY MEDICINE
2013年
29期
152-153
,共2页
高血压合并左室肥厚%老年%左旋氨氯地平%培哚普利%联合应用
高血壓閤併左室肥厚%老年%左鏇氨氯地平%培哚普利%聯閤應用
고혈압합병좌실비후%노년%좌선안록지평%배타보리%연합응용
Hypertension with left ventricular hypertrophy%Elderly%Amlodipine%Perindopril%Combined application
目的：观察左旋氨氯地平与培哚普利联合应用治疗老年高血压合并左室肥厚的临床疗效。方法将收治的120例高血压合并左室肥厚老年患者随机分为2组，即观察组60例，对照组60例。对照组患者行苯磺酸左旋氨氯地平治疗，观察组患者行左旋氨氯地平与培哚普利联合应用治疗。结果治疗后，对照组和观察组患者24 h平均SBP、DBP水平较治疗前均明显下降（P＜0.01）。在组间比较上，治疗后较治疗前，观察组患者24 h平均SBP、DBP水平的下降幅度大于对照组（P>0.05）。治疗后，对照组和观察组患者平均PWT、IVS、LVDd和LVMI水平较治疗前均明显下降（P＜0.01）。在组间比较上，治疗后较治疗前，观察组患者平均PWT、IVS、LVDd和LVMI水平的下降幅度大于对照组（P>0.05）。结论左旋氨氯地平与培哚普利联合应用治疗老年高血压合并左室肥厚的疗效显著，值得临床推广应用。
目的：觀察左鏇氨氯地平與培哚普利聯閤應用治療老年高血壓閤併左室肥厚的臨床療效。方法將收治的120例高血壓閤併左室肥厚老年患者隨機分為2組，即觀察組60例，對照組60例。對照組患者行苯磺痠左鏇氨氯地平治療，觀察組患者行左鏇氨氯地平與培哚普利聯閤應用治療。結果治療後，對照組和觀察組患者24 h平均SBP、DBP水平較治療前均明顯下降（P＜0.01）。在組間比較上，治療後較治療前，觀察組患者24 h平均SBP、DBP水平的下降幅度大于對照組（P>0.05）。治療後，對照組和觀察組患者平均PWT、IVS、LVDd和LVMI水平較治療前均明顯下降（P＜0.01）。在組間比較上，治療後較治療前，觀察組患者平均PWT、IVS、LVDd和LVMI水平的下降幅度大于對照組（P>0.05）。結論左鏇氨氯地平與培哚普利聯閤應用治療老年高血壓閤併左室肥厚的療效顯著，值得臨床推廣應用。
목적：관찰좌선안록지평여배타보리연합응용치료노년고혈압합병좌실비후적림상료효。방법장수치적120례고혈압합병좌실비후노년환자수궤분위2조，즉관찰조60례，대조조60례。대조조환자행분광산좌선안록지평치료，관찰조환자행좌선안록지평여배타보리연합응용치료。결과치료후，대조조화관찰조환자24 h평균SBP、DBP수평교치료전균명현하강（P＜0.01）。재조간비교상，치료후교치료전，관찰조환자24 h평균SBP、DBP수평적하강폭도대우대조조（P>0.05）。치료후，대조조화관찰조환자평균PWT、IVS、LVDd화LVMI수평교치료전균명현하강（P＜0.01）。재조간비교상，치료후교치료전，관찰조환자평균PWT、IVS、LVDd화LVMI수평적하강폭도대우대조조（P>0.05）。결론좌선안록지평여배타보리연합응용치료노년고혈압합병좌실비후적료효현저，치득림상추엄응용。
Objective To observe the clinical effect of combined application of amlodipine and perindopril in treatment of hypertension with left ventricular hypertrophy. Methods 120 patients with hypertension in our hospital with left ventricular hypertrophy in elderly patients were randomly divided into 2 groups, the observation group 60 cases, control group 60 cases. The control of Levamlodipine treatment group underwent, observe the combined group were treated with amlodipine and perindopril treatment. Results After the treatment, the observation group and the control group of patients with 24 h average SBP, DBP levels were signiifcantly decreased than before treatment (P<0.01). In the comparison between groups, after treatment than before treatment, patients in the observation group 24 h average SBP, DBP levels declined more than control group (P>0.05). After treatment, the observation group and the control group of patients with the average PWT, IVS, LVDd and LVMI levels were signiifcantly decreased than before treatment (P<0.01). In the comparison between groups, after treatment than before treatment, patients in the observation group the mean PWT, IVS, LVDd and LVMI level declined more than control group (P>0.05). Conclusion The curative effect of the combination of amlodipine and perindopril in elderly hypertensive patients with left ventricular hypertrophy signiifcantly, worthy of clinical application.
