中华实验和临床感染病杂志（电子版）
中華實驗和臨床感染病雜誌（電子版）
중화실험화림상감염병잡지（전자판）
CHINESE JOURNAL OF EXPERIMENTAL AND CLINICAL INFECTIOUS DISEASES(ELECTRONIC VERSION)
2013年
4期
499-501
,共3页
慢性鼻-鼻窦炎%鼻息肉%细菌学
慢性鼻-鼻竇炎%鼻息肉%細菌學
만성비-비두염%비식육%세균학
Chronic rhinosinusitis%Nasal polyps%Bacteriology
目的：比较伴和不伴鼻息肉的慢性鼻-鼻窦炎（CRS）患者前筛黏膜标本的细菌学特征。方法在鼻内镜手术中获取前筛黏膜标本，进行需氧和厌氧培养。结果本研究共纳入CRS患者135例，其中不伴鼻息肉者65例（A组），伴鼻息肉者70例（B组）。细菌培养总阳性率为85.2%（115/135）。A组和B组需氧或兼性厌氧细菌培养阳性率分别为87.7%（50/57）和82.9%（48/58），两组间分布无显著差异（χ2=0.562，P =0.454）。两组患者的黏膜标本以需氧菌和厌氧菌混合感染为主，混合感染率分别为78.9%（45/57）和79.3%（46/58），且差异无统计学意义（χ2=0.002，P =0.962）；两组最常见需氧菌株均为凝固酶阴性葡萄球菌和棒状杆菌属细菌。A组和B组厌氧菌培养阳性率分别为80.7%（46/57）和81.0%（47/58），差异无统计学意义（χ2=0.002，P=0.964）；最常见厌氧菌株为丙酸杆菌属细菌和消化链球菌属细菌。结论伴和不伴鼻息肉的CRS患者前筛黏膜标本的细菌学特征无明显差异。
目的：比較伴和不伴鼻息肉的慢性鼻-鼻竇炎（CRS）患者前篩黏膜標本的細菌學特徵。方法在鼻內鏡手術中穫取前篩黏膜標本，進行需氧和厭氧培養。結果本研究共納入CRS患者135例，其中不伴鼻息肉者65例（A組），伴鼻息肉者70例（B組）。細菌培養總暘性率為85.2%（115/135）。A組和B組需氧或兼性厭氧細菌培養暘性率分彆為87.7%（50/57）和82.9%（48/58），兩組間分佈無顯著差異（χ2=0.562，P =0.454）。兩組患者的黏膜標本以需氧菌和厭氧菌混閤感染為主，混閤感染率分彆為78.9%（45/57）和79.3%（46/58），且差異無統計學意義（χ2=0.002，P =0.962）；兩組最常見需氧菌株均為凝固酶陰性葡萄毬菌和棒狀桿菌屬細菌。A組和B組厭氧菌培養暘性率分彆為80.7%（46/57）和81.0%（47/58），差異無統計學意義（χ2=0.002，P=0.964）；最常見厭氧菌株為丙痠桿菌屬細菌和消化鏈毬菌屬細菌。結論伴和不伴鼻息肉的CRS患者前篩黏膜標本的細菌學特徵無明顯差異。
목적：비교반화불반비식육적만성비-비두염（CRS）환자전사점막표본적세균학특정。방법재비내경수술중획취전사점막표본，진행수양화염양배양。결과본연구공납입CRS환자135례，기중불반비식육자65례（A조），반비식육자70례（B조）。세균배양총양성솔위85.2%（115/135）。A조화B조수양혹겸성염양세균배양양성솔분별위87.7%（50/57）화82.9%（48/58），량조간분포무현저차이（χ2=0.562，P =0.454）。량조환자적점막표본이수양균화염양균혼합감염위주，혼합감염솔분별위78.9%（45/57）화79.3%（46/58），차차이무통계학의의（χ2=0.002，P =0.962）；량조최상견수양균주균위응고매음성포도구균화봉상간균속세균。A조화B조염양균배양양성솔분별위80.7%（46/57）화81.0%（47/58），차이무통계학의의（χ2=0.002，P=0.964）；최상견염양균주위병산간균속세균화소화련구균속세균。결론반화불반비식육적CRS환자전사점막표본적세균학특정무명현차이。
Objective To compare the bacteriologic features of anterior ethmoidal biopsy specimens between chronic rhinosinusitis patients without nasal polyps (group A) and with nasal polyps (group B). Method The biopsy specimens obtained during the nasal endoscopic surgery were cultured for aerobic and anaerobic bacteria. Results Total of 135 biopsy subjects were included, with 65 subjects without nasal polyps in group A and 70 subjects with nasal polyps in group B. In this cohort, the total bacterial culture positive rate was 85.2% (115/135), and the positive rate of aerobe or facultative anaerobe culture were 87.7%(50/57) in group A and 82.9%(48/58) in group B, without signiifcant difference (χ2 =0.562, P=0.454). Mixed growth of aerobe and anaerobe bacteria were mainly detected in the biopsy specimens and the positive rate were 78.9%(45/57) in group A and 79.3%(46/58) in group B, without signiifcant difference (χ2 = 0.002, P = 0.962). The most common aerobe bacteria were coagulase-negative staphylococci and corynebacterium species. The positive rate of anaerobic bacteria culture were similar between two groups (χ2=0.002, P=0.964), with 80.7%(46/57) in group A and 81.0%(47/58) in group B;and propionibacterium and peptostreptococcus species were the most common anaerobes. Conclusions There are no signiifcant differences in the bacteriologic features of ethmoidal biopsy specimens between chronic rhinosinusitis patients with and without nasal polyps.
