CAJ | 학술논문

目的：探讨中药熏洗对直肠癌术后肛门坠胀的影响。方法：将90例直肠癌腹会阴联合直肠癌根治术术后有肛门坠胀的患者随机分为对照组和治疗组各45例。对照组应用1：5000高锰酸钾液2000 ml坐浴,每日2次,连用15 d；治疗组应用中药熏洗配以熏洗护理措施,每日2次,15 d为1个疗程。观察2组临床疗效以及治疗前后血浆5-羟色胺(5-HT)﹑组胺(HA)﹑前列腺素E2(PGE2)水平和血常规和肝肾功能变化。结果：治疗组总有效率明显高于对照组(P<0.05)；治疗组和对照组血浆5-HT﹑HA和PGE2水平均明显降低,但治疗组优于对照组(P<0.05)；2组治疗前后血常规和肝肾功能无明显差异。结论：中药熏洗配以熏洗护理措施可明显降低血浆炎性介质的释放及循环水平,显著改善直肠癌腹会阴联合直肠癌根治术术后患者的肛门坠胀,安全,值得临床推广运用。
목적：탐토중약훈세대직장암술후항문추창적영향。방법：장90례직장암복회음연합직장암근치술술후유항문추창적환자수궤분위대조조화치료조각45례。대조조응용1：5000고맹산갑액2000 ml좌욕,매일2차,련용15 d；치료조응용중약훈세배이훈세호리조시,매일2차,15 d위1개료정。관찰2조림상료효이급치료전후혈장5-간색알(5-HT)﹑조알(HA)﹑전렬선소E2(PGE2)수평화혈상규화간신공능변화。결과：치료조총유효솔명현고우대조조(P<0.05)；치료조화대조조혈장5-HT﹑HA화PGE2수평균명현강저,단치료조우우대조조(P<0.05)；2조치료전후혈상규화간신공능무명현차이。결론：중약훈세배이훈세호리조시가명현강저혈장염성개질적석방급순배수평,현저개선직장암복회음연합직장암근치술술후환자적항문추창,안전,치득림상추엄운용。
ObjectiveTo explore the effects of fumigation of Chinese medicine and nursing care on anus dis-tentin after rectal carcinoma operation. Methods 90 patients with rectal cancer accompanied by anus distentin after abdominoperineal radical operation of rectal cancer were randomly divided into control group (45 cases) and treatment group (45 cases). Patients in control group received hip bath with 2000 ml potassium permanganate ;fumigation of Chinese medicine and nursing care were applied in the treatment group, clinical effects, changes of plasma 5-hydroxytryptamine (5-HT), histamine (HA),and prostaglandin E2 (PGE2), liver and renal functions and blood routine before and after treatment were observed and compared. ResultsThe total effective rate of treat-ment group was higher (P < 0.05). Plasma 5-HT, HA and PGE2 levels were decreased after treatment in both groups and the levels in treatment group were lower than in control group (P< 0.05). Conclusion Fumigation therapy of Chinese medicine plus nursing care can significantly decrease plasma inflammatory mediators and re-duce anus distention in patients with rectal cancer after radical operation.It is safe and worth popularizing in the clinical practice.