泸州医学院学报
瀘州醫學院學報
로주의학원학보
JOURNAL OF LUZHOU MEDICAL COLLEGE
2013年
5期
470-472
,共3页
儿童多发性抽动症%疏肝活络养阴法%氟哌啶醇%临床疗效
兒童多髮性抽動癥%疏肝活絡養陰法%氟哌啶醇%臨床療效
인동다발성추동증%소간활락양음법%불고정순%림상료효
Children tourette syndrome%Liver soothing-collateral-activating-Yin-nourishing method%Haloperidol%Clinical curative effect
目的：比较中药疏肝活络养阴法和氟哌啶醇治疗儿童多发性抽动症的临床疗效。方法：将108例儿童多发性抽动症患儿随机分为中药治疗组54例和西药对照组54例,中药治疗组每次50~100 ml,1日3次,每日1剂；西药对照组口服氟哌啶醇治疗,2组均治疗8周。按照耶鲁综合抽动严重程度量表（YGTSS)标准进行疗效评价,并观察治疗前后疗效及。结果：两组治疗前后自身对照YGTSS评分比较差异有统计学意义（P<0.05),组间比较差异无统计学意义（P>0.05)。两组疗前疗后用尼莫地平法评分,中药治疗组总有效率为87.04%,西药对照组总有效率为83.33%,2组间疗效对比差异无统计学意义（P>0.05)。结论：中药疏肝活络养阴法治疗儿童多发性抽动症较之西药氟哌啶醇可取得相当的临床疗效,鉴于西药氟哌啶醇副作用较大,笔者建议可在临床上使用中药疏肝活络养阴法治疗本病。
目的：比較中藥疏肝活絡養陰法和氟哌啶醇治療兒童多髮性抽動癥的臨床療效。方法：將108例兒童多髮性抽動癥患兒隨機分為中藥治療組54例和西藥對照組54例,中藥治療組每次50~100 ml,1日3次,每日1劑；西藥對照組口服氟哌啶醇治療,2組均治療8週。按照耶魯綜閤抽動嚴重程度量錶（YGTSS)標準進行療效評價,併觀察治療前後療效及。結果：兩組治療前後自身對照YGTSS評分比較差異有統計學意義（P<0.05),組間比較差異無統計學意義（P>0.05)。兩組療前療後用尼莫地平法評分,中藥治療組總有效率為87.04%,西藥對照組總有效率為83.33%,2組間療效對比差異無統計學意義（P>0.05)。結論：中藥疏肝活絡養陰法治療兒童多髮性抽動癥較之西藥氟哌啶醇可取得相噹的臨床療效,鑒于西藥氟哌啶醇副作用較大,筆者建議可在臨床上使用中藥疏肝活絡養陰法治療本病。
목적：비교중약소간활락양음법화불고정순치료인동다발성추동증적림상료효。방법：장108례인동다발성추동증환인수궤분위중약치료조54례화서약대조조54례,중약치료조매차50~100 ml,1일3차,매일1제；서약대조조구복불고정순치료,2조균치료8주。안조야로종합추동엄중정도량표（YGTSS)표준진행료효평개,병관찰치료전후료효급。결과：량조치료전후자신대조YGTSS평분비교차이유통계학의의（P<0.05),조간비교차이무통계학의의（P>0.05)。량조료전료후용니막지평법평분,중약치료조총유효솔위87.04%,서약대조조총유효솔위83.33%,2조간료효대비차이무통계학의의（P>0.05)。결론：중약소간활락양음법치료인동다발성추동증교지서약불고정순가취득상당적림상료효,감우서약불고정순부작용교대,필자건의가재림상상사용중약소간활락양음법치료본병。
ObjectiveTo compare the clinical curative effect of Haloperidol and the Chinese herbs of sooth-ing the liver, activating collterals and nourishing Yin on children with Tourette syndrome. Methods108 cases of children with Tourette syndrome were randomly divided into treatment group (54 cases),received Chinese herbs decoction, and control group (54 cass),received oral haloperidol. Yale YGTSS was used to evaluate the treatment effect. Results YGTSS rating of both groups before and after treatment had significant difference (P< 0.05),but no significant difference was found between the two groups after treatment (P> 0.05). The total effective rate of the treatment group and control group was 87.04% and 83.33%, with no significant difference. ConclusionChinese medicine and Western medicine haloperidol in the treatment of Tourette syndrome in children may make comparable clinical efficacy, but the clinical side effects of Chinese medicines are significantly less than haloperidol,which is worth to be recommended.
