黑龙江医药
黑龍江醫藥
흑룡강의약
HEILONGJIANG MEDICAL JOURNAL
2013年
5期
862-864
,共3页
高效液相色谱法%葡萄糖注射液%多种微量元素注射液%5-羟甲基糠醛%配伍
高效液相色譜法%葡萄糖註射液%多種微量元素註射液%5-羥甲基糠醛%配伍
고효액상색보법%포도당주사액%다충미량원소주사액%5-간갑기강철%배오
HPLC%Glucose injection%Multi-trace elements injection%5-hydroxymethylfurfural%Compatibility
目的：考察葡萄糖注射液与多种微量元素注射液配伍的稳定性。方法：采用高效液相色谱法测定配伍液中5-羟甲基糠醛的含量变化，同时观察和检测配伍液的外观、pH值、葡萄糖含量及不溶性微粒变化。结果：室温8 h内配伍液外观、pH值、葡萄糖含量及不溶性微粒，5-羟甲基糠醛含量均无明显变化。结论：葡萄糖注射液与多种微量元素注射液配伍后于室温下8h内可使用。
目的：攷察葡萄糖註射液與多種微量元素註射液配伍的穩定性。方法：採用高效液相色譜法測定配伍液中5-羥甲基糠醛的含量變化，同時觀察和檢測配伍液的外觀、pH值、葡萄糖含量及不溶性微粒變化。結果：室溫8 h內配伍液外觀、pH值、葡萄糖含量及不溶性微粒，5-羥甲基糠醛含量均無明顯變化。結論：葡萄糖註射液與多種微量元素註射液配伍後于室溫下8h內可使用。
목적：고찰포도당주사액여다충미량원소주사액배오적은정성。방법：채용고효액상색보법측정배오액중5-간갑기강철적함량변화，동시관찰화검측배오액적외관、pH치、포도당함량급불용성미립변화。결과：실온8 h내배오액외관、pH치、포도당함량급불용성미립，5-간갑기강철함량균무명현변화。결론：포도당주사액여다충미량원소주사액배오후우실온하8h내가사용。
Objective To study the stability of Glucose injection with Multi-trace elements Injection.Method:The content of 5-hydroxymethylfurfural were determined at different time by HPLC;the appearance of the solution was observed , its pH value, the content of glucose and particulate matter was determined.Re-sults:No signifycant differences were noted for the mixture in con-tents, appearance, pH value and particulate matter within 8 hours af-ter mixing.Conclusion:The mixture of Glucose iniection and Multi-trace elements iniection can be mixed to use within 8h under room temperature.
