CAJ | 학술논문

目的：观察抗生素加常规疗法治疗消化性溃疡并幽门梗阻的临床效果。方法46例消化性溃疡并幽门梗阻患者随机分为两组，各23例。对照组给予胃肠减压、维持水电解质平衡等对症支持治疗，同时给予奥美拉唑、丽珠得乐治疗；观察组在对照组的基础上加用阿莫西林、甲硝唑治疗，观察对比两组患者临床疗效。结果观察组总有效率高于对照组（P ＜0．05），复发率低于对照组（ P ＜0．01）。结论抗生素加常规疗法治疗消化性溃疡并幽门梗阻临床疗效明显，安全有效且复发率低，值得临床推广应用。
목적：관찰항생소가상규요법치료소화성궤양병유문경조적림상효과。방법46례소화성궤양병유문경조환자수궤분위량조，각23례。대조조급여위장감압、유지수전해질평형등대증지지치료，동시급여오미랍서、려주득악치료；관찰조재대조조적기출상가용아막서림、갑초서치료，관찰대비량조환자림상료효。결과관찰조총유효솔고우대조조（P ＜0．05），복발솔저우대조조（ P ＜0．01）。결론항생소가상규요법치료소화성궤양병유문경조림상료효명현，안전유효차복발솔저，치득림상추엄응용。
Objective To observe the clinical effect of antibiotics plus routine therapy in treatment of peptic ulcer and pyloric obstruction.Methods 46 patients with peptic ulcer and pyloric obstruction as the research objects were randomly divided into two groups .Control group was given gastrointestinal decompression , water and electrolyte balance and systemic support treatment were maintained ,and at the same time Lizhudele and Omeprazole were given .On the basis of the control group ,the observation group was giv-en amoxicillin and metronidazole to compare and observe the clinical curative effect of post -treatment of the two groups .Re sults The observation group had a higher rate of total efficacy ( P <0.05), but a lower rate of recurrence rate ( P <0.01) than the control group.Conclusion Antibiotics with conventional therapy in treatment of peptic ulcer and pyloric obstruction is safe and has obvious clinical curative effect with a lower rate of relapse ,which is clinically worthy .