CAJ | 학술논문

目的：探讨中西医结合治疗隆起型糜烂性胃炎的临床应用价值。方法以我院收治的86例南方某部队军人隆起型糜烂性胃炎为研究对象，随机法分为治疗组（45例）和对照组（41例）。对照组采用单纯西药治疗，治疗组应用西药联合中成药（胃特安片）疗法，对比分析两组患者临床症状和胃镜表现改善程度、组织病理学变化以及幽门螺杆菌（ Hp）根除率。结果临床总的疗效：治疗组有效率（91．1％）明显高于对照组（73．2％），两组有效率有显著差异（P＜0．05）。胃镜疗效：治疗组有效率88．9％（40/45）显著高于对照组70．7％（29/41），两组有效率有显著差异（P＜0．05）。病理疗效：治疗组胃黏膜活动性炎症、腺体萎缩、肠上皮化生等病理征象改善较明显；治疗组有效率83．8％（31/37）显著高于对照组61．3％（19/31），两组有效率有显著差异（P＜0．05）。 Hp根除率：治疗组（80．6％）与对照组（75.0％）相比，无显著性差异（P＞0．05）。结论西药联合胃特安片治疗隆起型糜烂性胃炎疗效较好。
목적：탐토중서의결합치료륭기형미란성위염적림상응용개치。방법이아원수치적86례남방모부대군인륭기형미란성위염위연구대상，수궤법분위치료조（45례）화대조조（41례）。대조조채용단순서약치료，치료조응용서약연합중성약（위특안편）요법，대비분석량조환자림상증상화위경표현개선정도、조직병이학변화이급유문라간균（ Hp）근제솔。결과림상총적료효：치료조유효솔（91．1％）명현고우대조조（73．2％），량조유효솔유현저차이（P＜0．05）。위경료효：치료조유효솔88．9％（40/45）현저고우대조조70．7％（29/41），량조유효솔유현저차이（P＜0．05）。병리료효：치료조위점막활동성염증、선체위축、장상피화생등병리정상개선교명현；치료조유효솔83．8％（31/37）현저고우대조조61．3％（19/31），량조유효솔유현저차이（P＜0．05）。 Hp근제솔：치료조（80．6％）여대조조（75.0％）상비，무현저성차이（P＞0．05）。결론서약연합위특안편치료륭기형미란성위염료효교호。
Objective To explore the clinical application of integrated traditional Chinese and Western medicine therapy in patients with erosive gastritis protuberance .Methods 86 southern army patients diagnosed as erosive gastritis protuberance in our hos-pital were chosen as research object .These patients were randomly divided into treatment group (45 cases) and control group (41 ca-ses) .The control group was treated with western medicine alone ,while the treatment group was given combination therapy of Western medicine and Chinese patent medicines ( Weitean tablets ) .The response of clinical syndromes and gastroscopy manifestations ,patholog-ical changes ,and Helicobacter pylori ( Hp) clearance rate were evaluated and compared in both groups after treatment .Results The effective rate of total clinical response in the treatment group ( 91.1%) was significantly higher than that in the control group (73.2%),P<0.05.The effective rates of gastroscopy response in the treatment group and the control group were 88.9%(40/45) and 70.7%(29/41)respectively,which was significant difference in these two groups (P<0.05).The improvement of active gastric muco-sa inflammation ,glandular epithelium atrophy and intestinal metaplasia in the treatment group were more significant .The effect rate of pathological curative response in treatment group was significantly higher than that in the control group (83.8%vs 61.3%,P<0.05). There was no significant difference in Hp clearance rate between the treatment group and the control group (80.6% vs 75.0%,P>0.05).Conclusion The combination therapy of Western medicine and Weitean tablets is more effective .