CAJ | 학술논문

目的： PET/CT正电子发射计算机断层(Positron Emission Tomography)是一种功能分子影像设备，最常用的18F-FDG在心肌存活性、恶性肿瘤诊断显像中具有重要的应用价值。但在临床大范围应用18F-FDG的同时，也发现了它的局限性，为了拓展PET/CT应用范围，弥补18F-FDG的不足，满足临床需求。方法以GE公司生产的合成器为例，以自动化合成方式合成了几种常见的非FDG正电子显像剂。结果合成了包括13N-氨水、18F-FMISO、1 C-蛋氨酸等几种常见的非FDG正电子显像剂，进行质量控制。结合临床初步对志愿者进行了检查。结论本文合成的显像剂均对FDG的应用范围进行了拓展及补充。扫描图像清晰，病灶显示清楚，初步临床结果令人满意。
목적： PET/CT정전자발사계산궤단층(Positron Emission Tomography)시일충공능분자영상설비，최상용적18F-FDG재심기존활성、악성종류진단현상중구유중요적응용개치。단재림상대범위응용18F-FDG적동시，야발현료타적국한성，위료탁전PET/CT응용범위，미보18F-FDG적불족，만족림상수구。방법이GE공사생산적합성기위례，이자동화합성방식합성료궤충상견적비FDG정전자현상제。결과합성료포괄13N-안수、18F-FMISO、1 C-단안산등궤충상견적비FDG정전자현상제，진행질량공제。결합림상초보대지원자진행료검사。결론본문합성적현상제균대FDG적응용범위진행료탁전급보충。소묘도상청석，병조현시청초，초보림상결과령인만의。
Objective PositronEmissionTomography(PET/CT)isafunctionalmolecularimagingequipment.Themostcommonlyused 18F-FD G has significant application value valuable in im aging of cardiac m uscle survival and diagnosis of m alignant tum or.W ith the exten-siveclinicaluseof18F-FDG,ithasshownsomeboundedness.ThepaperaimstoexpandtheapplicationrangeofPET/CT andmakeupfor the insufficiency of 18F-FD G so as to m eet clinical dem and.Methods Synthesizer by G E w as taken as an exam ple to autom atically synthe-size several com m on non-FD G positron photographic developers.Results Several com m on non-FD G positron photographic developers such as 13N-am m onium ,18F-FM ISO ,1 C-m ethionine w ere synthesized w ith quality control.C hecks w ere m ade to volunteers together w ith clinic prelim inary.Conclusion The synthesized photographic developer in this paper expands and supplem ents the application range of FD G .The scanned im agery is distinct w ith clear lesion dem onstration,w hose clinic prelim inary results are satisfactory.