CAJ | 학술논문

目的：分析颅内静脉窦血栓形成(CVST)的危险因素及影响早期预后的相关因素。方法对68例CVST患者的临床资料进行回顾性分析。按改良Rankin量表(mRS)评分分为早期预后良好组与早期预后不良组。临床资料及其早期预后采用单因素和多因素Logistic回归分析。结果与结论68例CVST患者出院时早期预后良好37例(54.4%)，早期预后不良31例(45.6%)。单因素Logistic回归分析结果显示，妊娠相关、中枢神经系统感染、高同型半胱氨酸血症、眼部症状、意识障碍、肢体瘫痪、伴继发性脑梗死、伴脑室受压/中线移位/全脑水肿8项因素是早期预后不良的影响因素。多因素Logistic回归分析显示，妊娠相关、中枢神经系统感染、高同型半胱氨酸血症、意识障碍、伴脑室受压/中线移位/全脑水肿是早期预后不良的独立影响因素。
목적：분석로내정맥두혈전형성(CVST)적위험인소급영향조기예후적상관인소。방법대68례CVST환자적림상자료진행회고성분석。안개량Rankin량표(mRS)평분분위조기예후량호조여조기예후불량조。림상자료급기조기예후채용단인소화다인소Logistic회귀분석。결과여결론68례CVST환자출원시조기예후량호37례(54.4%)，조기예후불량31례(45.6%)。단인소Logistic회귀분석결과현시，임신상관、중추신경계통감염、고동형반광안산혈증、안부증상、의식장애、지체탄탄、반계발성뇌경사、반뇌실수압/중선이위/전뇌수종8항인소시조기예후불량적영향인소。다인소Logistic회귀분석현시，임신상관、중추신경계통감염、고동형반광안산혈증、의식장애、반뇌실수압/중선이위/전뇌수종시조기예후불량적독립영향인소。
Objective To analyze the risk factors and early prognosis factors of cerebral venous sinus thrombosis (CVST). Methods 68 patients with CVST were analyzed retrospectively. The patients were divided into early favorable prognosis group and early unfavorable prognosis group according to modified Rankin Scale (mRS). The clinical data and prognosis were analyzed by univariate analysis and multi-variate logistic regression analysis. Results and Conclusion On discharge, there were 37(54.4%) cases and 31(45.6%) cases in the early fa-vorable prognosis group and the early unfavorable prognosis group respectively. Univariate analysis showed that 8 factors, including preg-nancy-associated factors, central nervous system infection, hyperhomocysteinemia, ocular symptoms, disturbance of consciousness, limb pa-ralysis, secondary cerebral infarction and ventricular compression/midline shift/encephaledema were associated with the early prognosis. Multivariate logistic regression analysis showed that pregnancy-associated factors, central nervous system infection, hyperhomocysteinemia, disturbance of consciousness and ventricular compression/midline shift/encephaledema were the independent factors.