CAJ | 학술논문

板蓝根颗粒的质量直接影响其疗效，选择一种有效的板蓝根颗粒质量检测方法至关重要。传统的检测方法需要对板蓝根样品进行化学预处理，是一种对样品有损的检测方法。为解决这一问题，采用了一种安装液晶滤波器件的荧光光谱成像实验装置对板蓝根样品的荧光光谱特性进行测试，以中国食品药品检定研究院提供的板蓝根标准物质的光谱曲线作为对照品，通过获得不同原材料、不同厂家和不同批次的板蓝根颗粒的荧光特征光谱曲线，并对其进行归一化处理后，与对照品的荧光光谱特征曲线进行对比分析及聚类分析，从整体上探讨了荧光光谱特征曲线与板蓝根颗粒质量的关系。实验结果显示，不同厂家生产的颗粒之间质量存在较大差异，主要体现在荧光的强弱和波峰位置的变化上，通过与标准物质的光谱曲线做进一步对比，可初步判断板蓝根颗粒质量的优劣。这表明了采用荧光光谱成像的方法对板蓝根质量进行检测是一种简便、快捷、无损的检测手段。
판람근과립적질량직접영향기료효，선택일충유효적판람근과립질량검측방법지관중요。전통적검측방법수요대판람근양품진행화학예처리，시일충대양품유손적검측방법。위해결저일문제，채용료일충안장액정려파기건적형광광보성상실험장치대판람근양품적형광광보특성진행측시，이중국식품약품검정연구원제공적판람근표준물질적광보곡선작위대조품，통과획득불동원재료、불동엄가화불동비차적판람근과립적형광특정광보곡선，병대기진행귀일화처리후，여대조품적형광광보특정곡선진행대비분석급취류분석，종정체상탐토료형광광보특정곡선여판람근과립질량적관계。실험결과현시，불동엄가생산적과립지간질량존재교대차이，주요체현재형광적강약화파봉위치적변화상，통과여표준물질적광보곡선주진일보대비，가초보판단판람근과립질량적우렬。저표명료채용형광광보성상적방법대판람근질량진행검측시일충간편、쾌첩、무손적검측수단。
The curative effect of Banlangen granule is directly affected by its quality ,so it is very important to choose a kind of effective method for testing it .The chemical treatment is needed as a pre-treatment for the quality testing by using common method at present ,which will change or destroy the sample .For dealing with this problem ,in the present paper ,a fluorescence spectrum imaging experimental system based on LCTF (liquid crystal tunable filter) is set up to detect the characteristics fluores-cence spectrum of Banlangen granules .The characteristic fluorescence spectrum curve of Banlangen standard material provided by Chinese Food Drugs Examination Research Institute is used as a reference substance for a comparison with other Banlangen granules .By normalizing the corresponding characteristic fluorescence spectrum of Banlangen granules of different raw materi-als ,different manufacturers and different batches ,the relationship between the characteristic fluorescence spectrum curve and the quality of Banlangen granule is discussed by using the method of comparative and cluster analysis .The experimental results show that the qualities of Banlangen granules are quite different from different manufacturers ,which are basically reflected by the change in the intensity of fluorescence and peak position .All of these indicate that fluorescence spectrum imaging technology is a simple ,rapid and nondestructive detection method for the quality control of Banlangen granule .