CAJ | 학술논문

目的：通过分析承德地区幽门螺杆菌（helicobacter pylori，H .pylori）临床分离珠对多种抗菌药物的敏感性，指导临床对于 H pylori根除治疗时的药物选择，提高根除率。方法用Kirby-Bauer药敏纸片法对108珠H pylori分别进行9种抗生素的药敏试验，并对药敏结果进行分析，得出相应的结果。结果 H pylori对阿莫西林/克拉维酸钾、阿莫西林的敏感率为100%，对甲硝唑、呋喃唑酮、克拉霉素、左氧氟沙星、四环素、米诺环素、氨苄西林的敏感率为76.9%、18.5%、9.3%、40.7%、8.3%、11.1%、37.8%。结论承德地区H pylori对阿莫西林/克拉维酸钾、阿莫西林、克拉霉素的敏感率高，可推荐为临床首选药物。对甲硝唑、左氧氟沙星、氨苄西林敏感率较低，不建议常规使用。
목적：통과분석승덕지구유문라간균（helicobacter pylori，H .pylori）림상분리주대다충항균약물적민감성，지도림상대우 H pylori근제치료시적약물선택，제고근제솔。방법용Kirby-Bauer약민지편법대108주H pylori분별진행9충항생소적약민시험，병대약민결과진행분석，득출상응적결과。결과 H pylori대아막서림/극랍유산갑、아막서림적민감솔위100%，대갑초서、부남서동、극랍매소、좌양불사성、사배소、미낙배소、안변서림적민감솔위76.9%、18.5%、9.3%、40.7%、8.3%、11.1%、37.8%。결론승덕지구H pylori대아막서림/극랍유산갑、아막서림、극랍매소적민감솔고，가추천위림상수선약물。대갑초서、좌양불사성、안변서림민감솔교저，불건의상규사용。
Objective Through the analysis of clinical isoates of helicobacter pylori (H pylori)Chengde beads antimicrobial susceptibility to a variety of clinical drug of choice for treatment of H pylori eradication,to improve eradication rates.Methods Susceptibility using the Kirby-auer disk dif usion method against 108 clincial isolates of H pylori pearl beads were performed in nine of antimicrobial susceptibility testing,and analyze the results.Results The profit sensitivity rate of H pylori to amocxicil in/ciavulanate、amoxicil in were100%to metronidazole、furazolidone、clarithromycin、levpfloxacin、minocycline、tetracycline a-nd ampicil in was76.9%、18.5%、9.3%、40.7%、8.3%、11.1%、37.8%.Concluion Chengde H pylori amoxicil ion/clavulanate potassium,amoxicil in sensitive rate,can be recommend-ed for clinical drug of choice, mertonidazole、levofloxacin、minocycline sensitive lower rate,was not recommended for routine use.