CAJ | 학술논문

目的：探讨国家级名老中医治疗肝病的用药规律。方法收集国家级名老中医治疗肝病处方，基于中医传承辅助系统软件构建数据库，采用关联规则 apriori 算法和复杂系统熵聚类方法，确定处方中各药物和药物组合的使用频数及药物之间的关联规则等。结果高频药物包括茵陈、茯苓、丹参、白术、柴胡等；高频药物组合包括“丹参，茯苓”、“白术，茯苓”、“丹参，茵陈”等；置信度为1的关联规则包括“大黄，虎杖→茵陈”、“大黄，郁金→茵陈”、“虎杖，栀子→茵陈”等。结论名老中医治疗肝病多用清热利湿、理气活血之品，配伍精巧合法。
목적：탐토국가급명로중의치료간병적용약규률。방법수집국가급명로중의치료간병처방，기우중의전승보조계통연건구건수거고，채용관련규칙 apriori 산법화복잡계통적취류방법，학정처방중각약물화약물조합적사용빈수급약물지간적관련규칙등。결과고빈약물포괄인진、복령、단삼、백술、시호등；고빈약물조합포괄“단삼，복령”、“백술，복령”、“단삼，인진”등；치신도위1적관련규칙포괄“대황，호장→인진”、“대황，욱금→인진”、“호장，치자→인진”등。결론명로중의치료간병다용청열리습、리기활혈지품，배오정교합법。
Objective To investigate the medication rules for the treatment of hepatopathy by national medical masters. Methods The prescriptions for hepatopathy were collected to build a database based on Traditional Chinese Medicine (TCM) inheritance assist system. After analyzed by the data mining, such as apriori algorithm and complex system entropy cluster, the frequency of single medicine and drug combinations that used in prescriptions, and the association rules among drugs were obtained. Results The most frequently used drugs were Herba Artemisiae Capillaris, Tuckahoe, Radix Salviae Miltiorrhizae, Rhizoma Atractylodis Macrocephalae, and Radix Bupleuri, et al. The most frequently used drug combinations were “Radix Salviae Miltiorrhizae, Tuckahoe”, “Rhizoma Atractylodis Macrocephalae, Tuckahoe”, and “Radix Salviae Miltiorrhizae, Herba Artemisiae Capillaris”, et al. And when the confidence of drug association rules was 1, the drug combinations were“Radix et Rhizoma Rhei, Giant Knotweed→Herba Artemisiae Capillaris”,“Radix et Rhizoma Rhei, Radix curcumae→Herba Artemisiae Capillaris”, “Giant Knotweed, Gardenia→Herba Artemisiae Capillaris” and so on. Conclusion The medicines were often with the actions of clearing heat, removing dampness, regulating qi and activating blood circulation, which were used for the treatment of hepatopathy by national medical masters.