中华内分泌外科杂志
中華內分泌外科雜誌
중화내분비외과잡지
CHINESE JOURNAL OF ENDOCRINE SURGERY
2014年
2期
163-166
,共4页
腹腔镜%卵巢成熟性畸胎瘤%免疫功能
腹腔鏡%卵巢成熟性畸胎瘤%免疫功能
복강경%란소성숙성기태류%면역공능
Laparoscopic operation%Ovarian benign teratoma%Immune function
目的：评价使用腹腔镜手术和开腹手术这2种不同术式剥除卵巢成熟性畸胎瘤对患者机体免疫功能的影响，为临床术式的选择提供更多的理论依据。方法收集卵巢成熟性畸胎瘤60例，30例行腹腔镜手术（腹腔镜组），30例行开腹手术（开腹手术组）。比较2组手术情况，检测术前、术后3 d及术后7 d，2组白细胞（WBC）和中性粒细胞（NEU）计数变化、IL-6、TNF-α和Th17细胞水平。结果腹腔镜组手术时间和术中出血量明显少于开腹手术组；2组术后3 d WBC和NEU计数、IL-6、TNF-α和Th17细胞均高于术前，且开腹手术组升高程度显著高于腹腔镜组，差异有统计学意义（P＜0.05）；术后7 d，以上观察指标在2组均有下降趋势，但开腹手术组仍明显高于腹腔镜组（ P＜0.05）。结论对于卵巢成熟性畸胎瘤，采用腹腔镜手术对患者免疫功能影响较小，有利于患者术后恢复。
目的：評價使用腹腔鏡手術和開腹手術這2種不同術式剝除卵巢成熟性畸胎瘤對患者機體免疫功能的影響，為臨床術式的選擇提供更多的理論依據。方法收集卵巢成熟性畸胎瘤60例，30例行腹腔鏡手術（腹腔鏡組），30例行開腹手術（開腹手術組）。比較2組手術情況，檢測術前、術後3 d及術後7 d，2組白細胞（WBC）和中性粒細胞（NEU）計數變化、IL-6、TNF-α和Th17細胞水平。結果腹腔鏡組手術時間和術中齣血量明顯少于開腹手術組；2組術後3 d WBC和NEU計數、IL-6、TNF-α和Th17細胞均高于術前，且開腹手術組升高程度顯著高于腹腔鏡組，差異有統計學意義（P＜0.05）；術後7 d，以上觀察指標在2組均有下降趨勢，但開腹手術組仍明顯高于腹腔鏡組（ P＜0.05）。結論對于卵巢成熟性畸胎瘤，採用腹腔鏡手術對患者免疫功能影響較小，有利于患者術後恢複。
목적：평개사용복강경수술화개복수술저2충불동술식박제란소성숙성기태류대환자궤체면역공능적영향，위림상술식적선택제공경다적이론의거。방법수집란소성숙성기태류60례，30례행복강경수술（복강경조），30례행개복수술（개복수술조）。비교2조수술정황，검측술전、술후3 d급술후7 d，2조백세포（WBC）화중성립세포（NEU）계수변화、IL-6、TNF-α화Th17세포수평。결과복강경조수술시간화술중출혈량명현소우개복수술조；2조술후3 d WBC화NEU계수、IL-6、TNF-α화Th17세포균고우술전，차개복수술조승고정도현저고우복강경조，차이유통계학의의（P＜0.05）；술후7 d，이상관찰지표재2조균유하강추세，단개복수술조잉명현고우복강경조（ P＜0.05）。결론대우란소성숙성기태류，채용복강경수술대환자면역공능영향교소，유리우환자술후회복。
Objective To evaluate the effect of laparoscopic operation and laparotomy on immune func -tion in divesting ovarian benign teratoma , and to provide further theoretical evidence for clinical practice .Meth-ods 60 patients with ovarian benign teratoma were selected .30 were conducted by laparoscopic operation ( lapa-roscopic group ) and 30 were conducted by laparotomy ( laparotomy group ) .Operation conditions were compared . White blood cell (WBC) and NEU counts, levels of IL-6,TNF-αand Th17 cells in the 2 groups before surgery, 3 days and 7 days after surgery were detected .Results Surgical time and intraoperative blood loss were signifi-cantly shorter and lower in laparoscopic group than in laparotomy group .Compared to those before surgery , WBC and NEU counts, levels of IL-6, TNF-αand Th17 cells in the two groups increased three days after surgery , and all of these observation targets were much higher in laparotomy group than in laparoscopic group (P<0.05).There were downtrends of all the observation targets in two groups 7 days after surgery .However , all the observation tar-gets were still significantly higher in laparotomy group than in laparoscopic group ( P<0.05) .Conclusion For o-varian benign teratoma , laparoscopic operation had less influence on immune function of patients compared with lap -arotomy, which is better for patients'recovery.
