CAJ | 학술논문

中药是复杂的多成分体系，其体内代谢过程则更为复杂。阐明中药的体内代谢产物及其分布浓度，是阐明中药药效物质的重要途径，也是临床用药的有力参考。近年来，很多学者针对中药复杂体系的体内代谢研究做出了有益的探索，建立了一系列新思路、新方法。本文将以典型研究为线索，探讨中药体内代谢研究的思路与方法。
중약시복잡적다성분체계，기체내대사과정칙경위복잡。천명중약적체내대사산물급기분포농도，시천명중약약효물질적중요도경，야시림상용약적유력삼고。근년래，흔다학자침대중약복잡체계적체내대사연구주출료유익적탐색，건립료일계렬신사로、신방법。본문장이전형연구위선색，탐토중약체내대사연구적사로여방법。
Traditional Chinese medicine (TCM) contains a big array of chemical constituents. These constituents un-dergo various metabolic reactions to produce complex in v iv o metabolites. Identification and distribution of these metabolites are important to reveal the "effective constituents" from a complex formulation. Recently, developments had been made to elucidate the complex metabolic process. In this review, we summarized the methods and strategies developed for TCM metabolism. Application of these metabolic results has also been discussed.