CAJ | 학술논문

目的：应用无创动态监护仪观察急性脑出血患者脑水肿动态变化。方法130例住院急性脑出血患者（均为发病24 h内入院），所有患者均于病程第1、3、5、7天采用无创脑水肿动态监护仪动态检测综合扰动系数。结果病程第1天表现为出血侧综合扰动系数低于健侧，3 d时患侧扰动系数升高，超过健侧，达到高峰，5 d时两侧接近，7 d时两侧基本正常。病程第3天、5天时患侧与健侧差异有统计学意义（ P＜0．01），第1天、7天患侧与健侧差异有统计学意义（P＜0．05）。脑出血患者血压水平与综合扰动系数的变化无明显关系，除自身患侧与健侧相比综合扰动系数差异有统计学意义外，两组不同血压水平之间综合扰动系数差异无统计学意义。结论急性出血性脑卒中患者综合扰动系数呈现先低后高的动态变化，反映了水肿形成过程及脑水肿发生的时间，包括脑水肿高峰期，及时反映脑内病灶周围组织水肿的动态变化，对急性脑出血患者的治疗有一定的指导意义。
목적：응용무창동태감호의관찰급성뇌출혈환자뇌수종동태변화。방법130례주원급성뇌출혈환자（균위발병24 h내입원），소유환자균우병정제1、3、5、7천채용무창뇌수종동태감호의동태검측종합우동계수。결과병정제1천표현위출혈측종합우동계수저우건측，3 d시환측우동계수승고，초과건측，체도고봉，5 d시량측접근，7 d시량측기본정상。병정제3천、5천시환측여건측차이유통계학의의（ P＜0．01），제1천、7천환측여건측차이유통계학의의（P＜0．05）。뇌출혈환자혈압수평여종합우동계수적변화무명현관계，제자신환측여건측상비종합우동계수차이유통계학의의외，량조불동혈압수평지간종합우동계수차이무통계학의의。결론급성출혈성뇌졸중환자종합우동계수정현선저후고적동태변화，반영료수종형성과정급뇌수종발생적시간，포괄뇌수종고봉기，급시반영뇌내병조주위조직수종적동태변화，대급성뇌출혈환자적치료유일정적지도의의。
Objective To observe the change of comprehensive agitating coefficient in the intracerebral hem -orrhage( ICH) patients monitoring by non-invasive cerebral edema and dynamical method ,and to find out dynamical change of cerebral edema in patients with ICH ,and to evaluate the specificity and sensitivity of non-invasive dynami-cal brain edema monitor in ICH treatment .Methods The change of comprehensive agitating coefficient in 130 patients was detected by non-invasive dynamical brain edema monitor at day 1,3,5 and 7 from ICH onset.Results The comprehensive agitating coefficient in focus side was lower than the unaffected side in both groups at the first day .The coefficient in the focus side was higher than the unaffected side at the third day ,and then became approximately equal at day 5 and basically normal at day 7.The comprehensive agitating coefficients in focus side were significantly differ-ent to unaffected side at day 3,5(P<0.01),and quite different at day 1,7(P<0.05).Conclusion The compre-hensive disturbance coefficient takes on dynamical changes in the ICH and reflects the course of edema formation . Cerebral edema monitoring by non-invasive and dynamical method can evaluate the course of cerebral edema ,and has a guiding role to the therapy of the ICH .